Methylprednisolone aceponate
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- CAS-Nr.
- 86401-95-8
- Englisch Name:
- Methylprednisolone aceponate
- Synonyma:
- SH-440;Advantan;ZK-91588;ZK-91-588;Aceponate;ZK-91588：SH-440;Prednisolone Impurity 21;METHYLPREDNISOLONE ACEPONATE;Methilprednisolone aceponate;Methylprednisolone Impurity 55
- CBNumber:
- CB2483146
- Summenformel:
- C27H36O7
- Molgewicht:
- 472.57
- MOL-Datei:
- 86401-95-8.mol
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Methylprednisolone aceponate Eigenschaften
- Schmelzpunkt:
- 105 - 108°C
- Siedepunkt:
- 595.8±50.0 °C(Predicted)
- Dichte
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Ethyl Acetate(Slightly)
- Aggregatzustand
- Solid
- pka
- 14.05±0.70(Predicted)
- Farbe
- White to Off-White
- InChIKey
- DALKLAYLIPSCQL-TXWHWSFMNA-N
- SMILES
- O(C(CC)=O)[C@]1(C(COC(C)=O)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(C=C[C@]4(C)[C@H]3[C@H](C[C@]12C)O)=O |&1:5,15,16,18,25,27,28,30,r|
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H361 |
Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Reproduktionstoxizit?t |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P281 |
Vorgeschriebene pers?nliche Schutzausrüstung verwenden. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Methylprednisolone aceponate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Methylprednisolone aceponate (MPA) is a new potent topical corticosteroid. Chemically, it is a corticosteroid diester that penetrates the skin rapidly. It is rapidly metabolised and then conjugated, so although potent, it does not appear to cause serious local or systemic side effects. Clinical trials have shown that once daily use is sufficient to control most eczematous conditions and is also appropriate and effective in atopic dermatitis. MPA is effective in the treatment of facial and scalp eczema and sunburn and has shown promising results in the treatment of psoriasis. MPA is also suitable for use in children and infants. MPA is available in a wide range of formulations (0.1%) including creams, ointments, fat ointments, lotions and solutions depending on the patient's individual condition.
Verwenden
Methylprednisolone aceponate used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.
Methylprednisolone aceponate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methylprednisolone aceponate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 126)Lieferanten
86401-95-8()Verwandte Suche:
- [(6s,8r,9r,10s,11s,13s,14s,17r)-17-(2-acetyloxyacetyl)-11-hydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl] propanoate
- METHYLPREDNISOLONE ACEPONATE
- Advantan
- ZK-91588：SH-440
- 11β-Hydroxy-6α-methyl-21-acetoxy-17-(propionyloxy)pregna-1,4-diene-3,20-dione
- 21-(Acetyloxy)-11β-hydroxy-6α-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- SH-440
- ZK-91588
- ZK-91-588
- 6α-Methyl Prednisolone Aceponate
- 6alpha-Methylprednisolone aceponate
- (6α，11β)-21-(Aeetoxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)pregna-14-dien-3，20-dione
- Aceponate
- (6S,8S,9S,10R,11S,13S,14S,17R)-17-(2-Acetoxyacetyl)-11-hydroxy-6,10,13-triMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
- Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-11-hydroxy-6-Methyl-17-(1-oxopropoxy)-, (6a,11b)-
- Methilprednisolone aceponate
- Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6α,11β)-
- Methylprednisolone aceponate Solution in Acetonitrile, 1000μg/mL
- Prednisolone Impurity 21
- Methylprednisolone AceponateQ: What is
Methylprednisolone Aceponate Q: What is the CAS Number of
Methylprednisolone Aceponate
- Methylprednisolone Impurity 55
- Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6α,11β)-
- 86401-95-8
- C27H36O7
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
- Steroid and Hormone
