Trinatrium-5-hydroxy-1-(4-sulfophenyl)-4-(4-sulfophenylazo)pyrazol-3-carboxylat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R42/43:Sensibilisierung durch Einatmen und Hautkontakt m?glich.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
FD & C Yellow No. 5 is principally the trisodium salt of 4,5-dihydro-5-oxo-l-(4-sulfophenyl)-4-[4-sulfophenyl-azo]-lH- pyrazole-3-carboxylic acid.
The colorant is a yellow-orange powder that dissolves in water to give a solution golden yellow at neutrality and in acid. When dissolved in concentrated sulfuric acid, it yields an orange-yellow solution that turns yellow when diluted with water.
FD & C Yellow No. 5 is regularly used in desserts (e.g., dessert powders, puddings, custards, gelatin, ice cream), candy, preserves, beverages (including carbonated soda beverages and flavored drink powders), prepared meats, and canned and frozen vegetables. It is also used in pharmaceuticals and cosmetics.1
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Chemische Eigenschaften
Deep yellow powder
Verwenden
Tartrazine is used as a dye for wool and silks; as colorant in food, drugs, and cosmetics. In biochemistry as an adsorption-elution indicator for chloride estimations. Tartrazine (otherwise known as E number E102, C.I.
19140, or FD&C Yellow 5) is a synthetic lemon yellow azo dye used as a food coloring. Tartrazine appears to cause the most allergic and intolerance reactions of all the azo dyes, particularly among as
thmatics and those with an aspirin intolerance.
synthetische
Commonly known??Tartmzine ?. (a) 4-Aminobenzenesulfonic acid diazo, and 5-Oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid coupled; (b) 2 Moore 4-Aminobenzenesulfonic acid?and dioxide 5 diacid reaction
Definition
ChEBI: An organic sodium salt which is the trisodium salt of tartrazine acid. A synthetic lemon yellow azo dye used as a food colouring.
Weltgesundheitsorganisation (WHO)
Tartrazine is widely used as a permitted colouring agent in food and pharmaceutical preparations. Its use has been associated with allergic
reactions some of which have been severe. Several national drug regulatory
authorities now require a warning on labels of products containing tartrazine and
some manufacturers have voluntarily withdrawn this compound from their
products.
Allgemeine Beschreibung
Tartrazine is a synthetic azo dye, commonly found in drugs, food products and cosmetics. It can be synthesized by the reaction of sulfanilic acid with 3-carboxy-l-(4-sulfophenyl)-5-pyrazolone.
Hazard
An allergen.
Sicherheitsprofil
Low toxicity by
ingestion. Mutation data reported. When
heated to decomposition it emits very toxic
fumes of NOx, SOx, and Na2O.
Toxikologie
This coloring agent is 5-hydroxy-1-p-sulfophenyl-4-(p-sulfophenylazo)- pyrazol-3-carboxylic acid, trisodium salt. It is a yellow powder and has been used as food coloring additive since 1916. Tartrazine is known as the least toxic coloring agent among synthetic coloring chemicals. The median acute oral lethal dose of tartrazine in mice is 12.17 g/kg. Beagle dogs received tartrazine as 2% of the diet for two years without adverse effects, with the possible exception of pyloric gastritis in one dog. Tumor incidence was unchanged relative to controls, in rats receiving tartrazine at 1.5% of the diet for 64 weeks, and in rats administered this dye at 5.0% of the diet for two years.
Human sensitivity to tartrazine has been reported with some frequency
and has been estimated to occur in 1/10,000 persons. Anaphylactic shock,
potentially life-threatening, has been reported but symptoms more commonly
cited are urticaria (hives), asthma, and purpura (blue or purple spots on the skin
or mucous membrane).
Trinatrium-5-hydroxy-1-(4-sulfophenyl)-4-(4-sulfophenylazo)pyrazol-3-carboxylat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
