[1R-[1α(R*),2β,4aβ,8aα]]-2-Hydroxy-α,2,5,5,8a-pentamethyl-α-vinyldecahydronaphthalin-1-propan-1-ol
|
|
- CAS-Nr.
- 515-03-7
- Bezeichnung:
- [1R-[1α(R*),2β,4aβ,8aα]]-2-Hydroxy-α,2,5,5,8a-pentamethyl-α-vinyldecahydronaphthalin-1-propan-1-ol
- Englisch Name:
- Sclareol
- Synonyma:
- SCIADONIC ACID;Natural sclareol;1-Naphthalenepropanol, α-ethenyldecahydro-2-hydroxy-α,2,5,5,8a-pentamethyl-, (αR,1R,2R,4aS,8aS)-;SCAREOL;SCLAREOL;Aids046592;Aids-046592;SCLAREOL(P);Sclareol 98%;SCLAREOL(RG)
- CBNumber:
- CB2173575
- Summenformel:
- C20H36O2
- Molgewicht:
- 308.51
- MOL-Datei:
- 515-03-7.mol
|
[1R-[1α(R*),2β,4aβ,8aα]]-2-Hydroxy-α,2,5,5,8a-pentamethyl-α-vinyldecahydronaphthalin-1-propan-1-ol Eigenschaften
- Schmelzpunkt:
- 95-100 °C (lit.)
- Siedepunkt:
- 218-220 °C/19 mmHg (lit.)
- alpha
- -13 º (c=4, in carbon tetrachloride)
- Dichte
- 0.954±0.06 g/cm3(Predicted)
- FEMA
- 4502 | (-)-SCLAREOL
- storage temp.
- 2-8°C
- L?slichkeit
- Chlorform, Ethyl Acetate (Slightly)
- pka
- 14.49±0.29(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Geruch (Odor)
- at 100.00 %. sweet balsam clary amber woody weedy
- Geruchsart
- balsamic
- Optische Aktivit?t
- [α]25/D 13°, c = 4 in carbon tetrachloride
- JECFA Number
- 2029
- BRN
- 2054148
- InChIKey
- XVULBTBTFGYVRC-HHUCQEJWSA-N
- LogP
- 5.54
- CAS Datenbank
- 515-03-7(CAS DataBase Reference)
- NIST chemische Informationen
- 1-Naphthalenepropanol, «alpha»-ethenyldecahydro-2-hydroxy-«alpha»,2,5,5,8a-pentamethyl-, [1r-[1«alpha»(r*),2«beta»,4a«beta»,8a«alpha»]]-(515-03-7)
- EPA chemische Informationen
- Sclareol (515-03-7)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
WGK Germany |
2 |
|
|
RTECS-Nr. |
QK0301900 |
|
|
HS Code |
29061990 |
|
|
Bildanzeige (GHS) |
|
Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
|
Sicherheit |
P264 |
Nach Gebrauch gründlich waschen. |
P264 |
Nach Gebrauch gründlich waschen. |
P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
P337+P313 |
Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
|
[1R-[1α(R*),2β,4aβ,8aα]]-2-Hydroxy-α,2,5,5,8a-pentamethyl-α-vinyldecahydronaphthalin-1-propan-1-ol Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Sclareol is used in biological studies as it has anti-inflammatory activity in both lipopolysaccharide-stimulated macophages and λ-carrageenan-induced paw edema model.
Definition
ChEBI: A labdane diterpenoid that is labd-14-ene substituted by hydroxy groups at positions 8 and 13. It has been isolated from Salvia sclarea.
Allgemeine Beschreibung
Sclareol, a diterpene compound with a labdane skeleton, is mainly used as a raw material in the fragrance industry. It shows potent cytotoxic and cytostatic effect in human leukemic cell lines.
Cytotoxicity
IC
50 (μg/mL): 16.6 (HeLa), 32.65 (MCF7),65.2 μM (MG63) (Farimani et al. 2014).
[1R-[1α(R*),2β,4aβ,8aα]]-2-Hydroxy-α,2,5,5,8a-pentamethyl-α-vinyldecahydronaphthalin-1-propan-1-ol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
MANOOL
1-Naphthalenepropanol,2-(acetyloxy)-a-ethenyldecahydro-a,2,5,5,8a-pentamethyl-,acetate,(aR,1R,2R,4aS,8aS)- (9CI)
Clary sage oil
Downstream Produkte
[1R-[1α(R*),2β,4aβ,8aα]]-2-Hydroxy-α,2,5,5,8a-pentamethyl-α-vinyldecahydronaphthalin-1-propan-1-ol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 370)Lieferanten
515-03-7([1R-[1α(R*),2β,4aβ,8aα]]-2-Hydroxy-α,2,5,5,8a-pentamethyl-α-vinyldecahydronaphthalin-1-propan-1-ol)Verwandte Suche:
- (1R,2R,8AS)-DECAHYDRO-1-(3-HYDROXY-3-METHYL-4-PENTENYL)-2,5,5,8A-TETRAMETHYL-2-NAPHTHOL
- SCLAREOL, NATURAL
- 1-Naphthalenepropanol, alpha-ethenyldecahydro-2-hydroxy-alpha,2,5,5,8A-pentamethyl-, (alphar,1R,2R,4as,8as)-: (1R,2R,4as,8as)-1-[(3R)-3-hydroxy-3-methylpent-4-en-1-yl]-2,5,5,8A-tetramethyldecahydronaphthalen-2-ol
- Aids046592
- Aids-046592
- SALSOLINOL HYDROBROMIDE(RG)(CALL)
- Sclareol,(1R,2R,8aS)-Decahydro-1-(3-hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyl-2-naphthol
- SCLAREOL
- (13r)-labd-14-ene-13-diol
- (1r-(1-alpha(r*),2-beta,4a-beta,8a-alpha))-thyl
- .alpha.-ethenyldecahydro-2-hydroxy-.alpha.,2,5,5,8a-pentamethyl-,[1R-[1.alpha.(R*),2.beta.,4a.beta1-Naphthalenepropanol
- [1theta-[1alpha(theta),2beta,4abeta,8aalpha]]-thyl
- 1-(3-Hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyldecahydro-2-naphthalenol
- 1-Naphthalenepropanol, alpha-ethenyldecahydro-2-hydroxy-alpha,2,5,5,8a-pentamethyl-, [1R-[1alpha(R*),2beta,4abeta,8aalpha]]-
- 1-naphthalenepropanol,alpha-ethenyldecahydro-2-hydroxy-alpha,2,5,5,8a-pentame
- (1R,2R,4aS,8aS)-1-((R)-3-hydroxy-3-Methylpent-4-en-1-yl)-2,5,5,8a-tetraMethyldecahydronaphthalen-2-ol
- Sclareol 98%
- 1-Naphthalenepropanol,a-ethenyldecahydro-2-hydroxy-a,2,5,5,8a-pentaMethyl-,(aR,1R,2R,4aS,8aS)-
- 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-2-hydroxy-.alpha.,2,5,5,8a-pentamethyl-, (.alpha.R,1R,2R,4aS,8aS)-
- SCLAREOL(P)
- SCLAREOL(RG)
- (1R-(1alpha(R*),2beta,4abeta,8aalpha))-2-Hydroxy-alpha,2,5,5,8a-pentamethyl-alpha-vinyldecahydronaphthalin-1-propan-1-ol
- .alpha.-ethenyldecahydro-2-hydroxy-.alpha.,2,5,5,8a-pentamethyl-, [1R-[1.alpha.(R*),2.beta.,4a.beta1-Naphthalenepropanol
- SCAREOL
- 1-Naphthalenepropanol, α-ethenyldecahydro- 2-hydroxy-α,2,5,5,8a-pentamethyl-, [1R-[1α(R),2,4a,8aα]]-
- Clary Sage Concrete
- Sclareol(Crude)
- 1-naphthalenepropanol,decahydro-alpha-ethenyl-2-hydroxy-alpha,2,5,5,8a-pentame
- Labd-14-ene-8,13-diol, (13R)-
- [1R-[1alpha(R*),2beta,4abeta,8aalpha]]-2-hydroxy-alpha,2,5,5,8a-pentamethyl-alpha-vinyldecahydronaphthalene-1-propan-1-ol
- SCLAREOL 95+%
- Sclareol 515-03-7
- Sclareol, 98%, Semi synthetic Semi synthetic
- Sclareol (~90%)
- Sclareol >
- (-)-Sclareol
- (1R,2R,4aS,8aS)-1-[(3R)-3-hydroxy-3-methylpent-4-enyl]-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol
- SCIADONIC ACID
- 1-Naphthalenepropanol, α-ethenyldecahydro-2-hydroxy-α,2,5,5,8a-pentamethyl-, (αR,1R,2R,4aS,8aS)-
- Natural sclareol
- Nano-Liposomal SCLAREOL, Water-Soluble SCLAREOL
- 1-Naphthalenepropanol, α-ethenyldecahydro-2-hydroxy-α,2,5,5,8a-pentamethyl-, (αR,1R,2R,4aS,8aS)-
- Sclareol in Acetone
- Salvia Sclarea Extract Sclareol Powder
- 515-03-7
- 0515-03-07
- C20H36O2C20H36O2
- Organic Building Blocks
- SA - SM
- Alphabetic
- Asymmetric Synthesis
- Chiral Building Blocks
- Analytical Standards
- Analytical Chromatography Product Catalog
- Polyols
- Inhibitors
- chemical reagent
- pharmaceutical intermediate