Cefacetril Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Pale Beige Solid
Antimicrobial activity
Its spectrum resembles that of cefalotin. Following an intramuscular
dose of 1 g, a peak plasma concentration around
15 mg/L is achieved at 1 h. About 25% is bound to plasma protein. Penetration into the CSF is limited. About 80% of
the drug is excreted in the urine, producing concentrations
in excess of 1 g/L, 25% of which is in the desacetylated form.
Clearance is depressed by probenecid and in renal failure.
Little is excreted in the bile.
Manifestations of hypersensitivity in patients not known
to be allergic to β-lactam antibiotics are common. It is no
longer used.
Cefacetril Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
