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Dihydromyricetin

Dihydromyricetin Struktur
27200-12-0
CAS-Nr.
27200-12-0
Englisch Name:
Dihydromyricetin
Synonyma:
ampeloptin;AMPELOPSIN;Two hydrogenMyricetin;vine tea extract dihydromyricetin;3,3’,4’,5,5’,7-hexahydroxy-flavanon;DihydroMyricetin, froM Myrica rubra;3,3’,4’,5,5’,7-hexahydroxy-2,3-dihydroflavanonol;2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on;3,3',4',5,5;,(2r-trans)-
CBNumber:
CB1670507
Summenformel:
C15H12O8
Molgewicht:
320.25
MOL-Datei:
27200-12-0.mol

Dihydromyricetin Eigenschaften

storage temp. 
-20°C
L?slichkeit
DMSO: ≥5mg/mL (warmed)
Aggregatzustand
powder
Siedepunkt:
780.7±60.0 °C(Predicted)
Dichte
1.808±0.06 g/cm3(Predicted)
Schmelzpunkt:
239-241 °C
pka
7.38±0.60(Predicted)
Farbe
white to beige
Stabilit?t:
Hygroscopic
InChI
InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
InChIKey
KJXSIXMJHKAJOD-LSDHHAIUSA-N
SMILES
[C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O
LogP
1.230 (est)
CAS Datenbank
27200-12-0

Sicherheit

S-S?tze: 24/25
WGK Germany  3
HS Code  29329990

Dihydromyricetin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound, which is found in large quantities in Asian plant species. One of them – Hovenia dulcis – is known for centuries in traditional Chinese medicine as a cure for alcohol poisoning and hangover (Liang et al. 2014). DHM is sold as a supplement and is commonly marketed as a treatment for hangovers due to its ability to reduce blood alcohol levels and projected hepatoprotective properties.
Dihydromyricetin had beneficial effects on health such as antimicrobial, anti-inflammatory,antioxidative, anticancer, lipid and glucose metabolism-regulatory activities,and cell death-mediating without or with minimum adverse effects on normal cells. And most importantly, DHM has been shown to provide significant hepatoprotective effects. Its positive influence on alcohol-induced and other liver diseases was suggested in the study of acute liver failure (Liu et al. 2017).

Verwenden

Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.

Definition

ChEBI: (+)-dihydromyricetin is an optically active form of dihydromyricetin having (2R,3R)-configuration. It has a role as a metabolite, an antioxidant and an antineoplastic agent. It is a secondary alpha-hydroxy ketone and a dihydromyricetin. It is an enantiomer of a (-)-dihydromyricetin.

Clinical Use

Dihydromyricetin can be used as a novel anti-alcoholism drug, clinically used to treat hangovers, fever, parasitic infections and liver disease. It is currently being studied in clinical trials for its effects on glycaemic control, insulin sensitivity and insulin secretion in type 2 diabetes.

Dihydromyricetin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dihydromyricetin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 450)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Changsha Staherb Natural Ingredients Co., Ltd.
+86-0731-84213302 +86-18374838656
info@staherb.cn China 1025 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Shaanxi LonierHerb Bio Technology Co Ltd
+86-86-+86-86-029-87551862 +8617702909819
sales006@ingredients-lonier.com China 2608 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
Changyi Longchang Bio-Chemical Co., LTD
+8613256193735
info@longchangchemical.com China 988 58
Hovane Phytochemicals Co., Ltd
+86-17340288373
victor.liu@hovane.com China 32 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5857 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630
bess@weibangbio.com China 18151 58
Bonerge(Hunan) Lifescience Co., Ltd.
+86-731-82791134 +86-17673622440
Alav.w@bonerge.com China 30 58

27200-12-0()Verwandte Suche:


  • (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
  • Dihydromyricetin (+)-Dihydromyricetin
  • Ampelopsin (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one
  • ampelopsin(flavanol)
  • DIHYDROMYRICETIN(RG)
  • 3,3’,4’,5,5’,7-hexahydroxyflavanone
  • (2R)-2,3-Dihydro-3β,5,7-trihydroxy-2α-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
  • (2R)-2α-(3,4,5-Trihydroxyphenyl)-3β,5,7-trihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
  • DihydroMyricetin(AMpeloptin)
  • DihydroMyricetin, AMpelopsin
  • (+)-Dihydromyricetin
  • (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one
  • (2r-trans)-2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benz
  • ,(2r-trans)-
  • aMpeloptin,(2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroMan-4-one
  • DIHYDROMYRICETIN
  • Ampelopsin(AMP)
  • Dihydromyricetin (DHM)
  • Dihydromyricetin, 98%, from Myrica rubra
  • 3,3',4',5,5
  • Nano Liposomal Dihydromyricetin
  • 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
  • Dihydromyricetin 27200-12-0
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R,3R)-
  • Dihydromyricetin 25%-98%
  • Dihydromyricetin,HPLC≥98%
  • Dihydromyricetin Powder 27200-12-0 Dihydromyricetin
  • Water-soluble DihydroMyricetin, Liposomal DihydroMyricetin
  • Vine Tea. Dihydromyricetin
  • Hovenia Dulcis Extract. Dihydromyricetin
  • 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on
  • 3,3’,4’,5,5’,7-hexahydroxy-2,3-dihydroflavanonol
  • 3,3’,4’,5,5’,7-hexahydroxy-flavanon
  • DihydroMyricetin, froM Myrica rubra
  • Two hydrogenMyricetin
  • ampeloptin
  • AMPELOPSIN
  • vine tea extract dihydromyricetin
  • dihydrromyricetin
  • Pea Protein 222400-29-5
  • Dihydrosalicylate
  • Dihydromyricetin Powder
  • DIHYDROMYRICETIN HCL
  • Dihydromyricetin-RM
  • 27200-12-0
  • C21H12O8
  • natural product
  • Inhibitors
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • chemical reagent
  • pharmaceutical intermediate
  • Flavanones
  • 27200-12-0
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