Acemetacin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S25:Berührung mit den Augen vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Beschreibung
Acemetacin is used in the treatment of pain
and restricted mobility resulting from chronic
articular rheumatism, degenerative articular disease, gout, and inflammation of muscle, joints,
and tendons. Acemetacin causes less gastrointestinal blood loss than indomethacin. Its anti-inflammatory activity results from liberation of
the parent compound, indomethacin.
Chemische Eigenschaften
Light Yellow Solid
Verwenden
Cyclo-oxygenase inhibitor; analgesic; anti-inflammatory.
Definition
ChEBI: A carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used in the treatment of rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activ
ty is due to both acemetacin and its major metabolite, indometacin.
Sicherheitsprofil
Poison by ingestion, subcutaneous,intraperitoneal, intravenous, and intramuscular routes. Anexperimental teratogen. Other experimental reproductiveeffects. When heated to decomposition it emits toxic fumesof Cl?? and NOx. An anti-inflammatory agent.
Acemetacin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
