3-(3,4-Dihydroxyphenyl)propionsure
|
|
|
- CAS-Nr.
- 1078-61-1
- Bezeichnung:
- 3-(3,4-Dihydroxyphenyl)propionsure
- Englisch Name:
- Dihydrocaffeic acid
- Synonyma:
- NSC 407275;NSC 624007;Hydrocaffeate;HYDROCAFFEIC ACID;3-propionic acid;DIHYDROCAFFEIC ACID;DIHYDROCAFFEIC ACID(RG);3,4-DIHYDROCAFFEIC ACID;13C6]-Dihydrocaffeic acid;4-Dihydroxyhydrocinnamic acid
- CBNumber:
- CB1439090
- Summenformel:
- C9H10O4
- Molgewicht:
- 182.17
- MOL-Datei:
- 1078-61-1.mol
|
3-(3,4-Dihydroxyphenyl)propionsure Eigenschaften
- Schmelzpunkt:
- 136-139 °C(lit.)
- Siedepunkt:
- 418℃
- Dichte
- 1.398
- Flammpunkt:
- 220℃
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 4.75±0.10(Predicted)
- Farbe
- Pale Beige to Pale Brown
- Wasserl?slichkeit
- Slightly soluble in water.
- BRN
- 2213449
- InChI
- InChI=1S/C9H10O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
- InChIKey
- DZAUWHJDUNRCTF-UHFFFAOYSA-N
- SMILES
- C1(CCC(O)=O)=CC=C(O)C(O)=C1
- LogP
- 0.115 (est)
- CAS Datenbank
- 1078-61-1(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
|
|
| R-S?tze: |
36/37/38 |
|
|
| S-S?tze: |
26-36 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
MW5143500 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
3-(3,4-Dihydroxyphenyl)propionsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Dihydrocaffeic acid is a polyphenol that has diverse biological activities, including antioxidant, neuroprotective, and enzyme inhibitory properties. Dihydrocaffeic acid scavenges ABTS (; IC
50 = 81.86 μg/ml) and 2,2-diphenyl-1-picrylhydrazyl (DPPH; ; IC
50 = 192.86 μg/ml) radicals and increases the survival of RGC-5 mouse retinal ganglion cells under hypoxic conditions and in the presence of S-nitroso-N-acetyl-D,L-penicillamine (SNAP; ) in a concentration-dependent manner. It also decreases endothelial nitric oxide synthase (eNOS) activity in EA.hy926 human endothelial cells in a concentration-dependent manner.
In vivo, dihydrocaffeic acid (30 mg/kg) decreases infarct size in a rat model of transient ischemia induced by middle cerebral artery occlusion (MCAO).
Chemische Eigenschaften
Brown Solid
Verwenden
Dihydrocaffeic Acid is a natural product containing a catechol group with an α,β-unsaturated carboxylic acid chain. Dihydrocaffeic Acid has been shown to have hepatoprotective activity. Dihydrocaffei
c Acid is a metabolite of Caffeic Acid (C08000) with potent antioxidant properties.
Definition
ChEBI: A monocarboxylic acid that is 3-phenylpropionic acid substituted by hydroxy groups at positions 3 and 4. It is a metabolite of caffeic acid and exhibits antioxidant activity.
3-(3,4-Dihydroxyphenyl)propionsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-(3,4-Dihydroxyphenyl)propionsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 257)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.
|
+86-18616643091 +86-18616643091
|
info@rochipharma.com |
China |
246 |
58 |
|
Jiangsu Guiren Medicine Co.,Ltd
|
+86-13815020719 +86-13815020719
|
guiren_medicine@163.com |
China |
154 |
58 |
|
Hebei Weibang Biotechnology Co., Ltd
|
+8615531157085
|
abby@weibangbio.com |
China |
8804 |
58 |
|
Hebei Mujin Biotechnology Co.,Ltd
|
+86 13288715578 +8613288715578
|
sales@hbmojin.com |
China |
12825 |
58 |
|
Hebei Chuanghai Biotechnology Co,.LTD
|
+86-13131129325
|
sales1@chuanghaibio.com |
China |
5887 |
58 |
|
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
+8613343047651
|
admin@zlchemi.com |
China |
3692 |
58 |
|
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
|
+8615373025980
|
clara@hbshengyang.com |
China |
895 |
58 |
|
Capot Chemical Co.,Ltd.
|
+86-（0）57185586718 +86-13336195806
|
sales@capot.com |
China |
29792 |
60 |
|
Shanghai Daken Advanced Materials Co.,Ltd
|
+86-371-66670886
|
info@dakenam.com |
China |
19902 |
58 |
|
Henan Tianfu Chemical Co.,Ltd.
|
+86-0371-55170693 +86-19937530512
|
info@tianfuchem.com |
China |
21632 |
55 |
1078-61-1(3-(3,4-Dihydroxyphenyl)propionsure)Verwandte Suche:
3-(3,4-Dihydroxyphenyl)propionsure
5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)-chinolin-7-carbons?ure
3-Hydroxy-D-tyrosin
Ethyl-3-(3,4,5-trimethoxyphenyl)propionat
[S-(R*,R*)]-4-[2-[2-Carboxy-5-(β-D-glucopyranosyloxy)-2,3-dihydro-6-hydroxy-1H-indol-1-yl]vinyl]-2,3-dihydropyridin-2,6-dicarbonsure
threo-β,3-Dihydroxy-DL-tyrosin
3-Hydroxy-L-tyrosin
3-(3,4-Dimethoxyphenyl)propionsure
3,4,5-Trimethoxyhydrozimtsure
Methyldopa
3-(3,4-Dihydroxyphenyl)-DL-alanin
Benzo-1,3-dioxol-5-propionsure
3-(4-Hydroxy-3-methoxyphenyl)propionsure
Ethyl-3-oxo-3-(3,4,5-trimethoxyphenyl)propionat
3-(4-Hydroxy-3,5-dimethoxyphenyl)propionsure
3-(2,3,4-Trimethoxyphenyl)propionsure
Ethyl-3-(4-hydroxy-3-methoxyphenyl)propionat
3,4-Dihydroxyzimtsure
- 3-(3,4-Dihydroxyphenyl)propionic acid, Hydrocaffeic acid
- 3-(3,4-Dihydroxyphenyl)propionic acid, 98+%
- DIHYDROCAFFEIC ACID(RG)
- 3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID
- 3,4-DIHYDROXYHYDROCINNAMIC ACID
- 3,4-DIHYDROCAFFEIC ACID
- BETA-(3,4-DIHYDROXYPHENYL) PROPIONIC ACID
- DIHYDROCAFFEIC ACID
- HYDROCAFFEIC ACID
- 3,4-dihydroxy-benzenepropanoicaci
- 3,4-dihydroxybenzenepropanoicacid
- 3,4-dihydroxy-hydrocinnamicaci
- 3,4-Dihydroxyhydrocinnamic acid~Hydrocaffeic acid
- 3,4-dihydroxyphenylpropionic acid
- 3-(3,4-Dihydroxyphenyl)propanoic acid
- 3-propionic acid
- 3,4-Dihydroxybenzenepropionic Acid
- 3,4-DihydroxydihydrocinnaMic Acid
- NSC 407275
- NSC 624007
- 3,4-Dihydroxy-beta-phenylpropionic acid
- 3-(3,4-dihydroxyphenyl)propanoate
- 4-Dihydroxyhydrocinnamic acid
- Benzenepropanoic acid, 3,4-dihydroxy-
- 3-(3,4-dihydroxyphenyl)propanoicaci
- 3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID USP/EP/BP
- 3- (3, 4-DIHYDROXYPHENYL) Propio Nic Acid / Dihydrocaffeic Acid Powder CAS 1078-61-1
- 13C6]-Dihydrocaffeic acid
- Hydrocaffeate
- Dihydrocaffeic acid, 10 mM in DMSO
- Dihydrocaffeic acid (3,4-dihydroxyphenylpropionic acid)
- 1078-61-1
- HO2C6H3CH2CH2CO2H
- Carboxylic Acids
- Carbonyl Compounds
- C9
- Building Blocks
- Organic Building Blocks
- Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- Aromatic Cinnamic Acids, Esters and Derivatives
