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GABEXATE

GABEXATE Struktur
39492-01-8
CAS-Nr.
39492-01-8
Englisch Name:
GABEXATE
Synonyma:
GABEXATE;Gabexate USP/EP/BP;GabexateMesylateBase;4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester;ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;diaminomethylidene-[6-(4-ethoxycarbonylphenoxy)-6-oxohexyl]ammonium;4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester;Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester;[N'-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium methanesulfonate
CBNumber:
CB1258637
Summenformel:
C16H23N3O4
Molgewicht:
321.37
MOL-Datei:
39492-01-8.mol

GABEXATE Eigenschaften

Siedepunkt:
472.2±55.0 °C(Predicted)
Dichte
1.20±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at RT
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
13.83±0.70(Predicted)
Farbe
White

Sicherheit

GABEXATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Gabexate mesylate is used in combination with somatostatin and octreotide in the treatment of severe acute pancreatitis in elderly patients.

Biologische Aktivit?t

Serine protease inhibitor; inhibits trypsin, plasmin, plasma kallikrein and thrombin (IC 50 values are 9.4, 30, 41 and 110 mM respectively). Antithrombotic in vitro and in vivo . Also inhibits LPS-induced TNF- α production, probably by inhibiting NF- κ B and AP-1 activation.

GABEXATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Natriumhydroxid Ethylbenzoat Thionyldichlorid Pyridin

Downstream Produkte

GABEXATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 30)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30231 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 22787 58
Sinoway Industrial co., ltd. 		0592-5800732; +8613806035118
 xie@china-sinoway.com China 986 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
9ding chemical ( Shanghai) Limited 4009209199
sales@9dingchem.com China 18209 56
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973
 sales@uhnshanghai.com China 1942 58
BOC Sciences --
 info@bocsci.com USA 0 65

39492-01-8()Verwandte Suche:

  • GABEXATE
  • GabexateMesylateBase
  • [N'-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium methanesulfonate
  • 4-[(6-Guanidinohexanoyl)oxy]benzoic acid ethyl ester
  • 4-[[6-[[Amino(imino)methyl]amino]-1-oxohexyl]oxy]benzoic acid ethyl ester
  • diaminomethylidene-[6-(4-ethoxycarbonylphenoxy)-6-oxohexyl]ammonium
  • Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester
  • Gabexate USP/EP/BP
  • ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate
  • 39492-01-8
  • Proteinase-activated receptor (PAR)
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