2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylatmonohydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Beschreibung

Nicardipine is a dihydropyridine L-type calcium channel antagonist that displays antihypertensive and antianginal activity. It is reported to inhibit adenosine A₁, A_2A, and A₃ receptors with K_i values of 19.6, 63.8, and 3.25 μM, respectively, and can inhibit cytochrome P450 3A4 catalytic activity with an IC₅₀ value of 0.148 μM. Additionally, nicardipine has been shown to activate transient receptor potential A1 channels, producing an increase in Ca²⁺ (EC₅₀ = 0.5 μM).

Chemische Eigenschaften

Yellow Solid

Verwenden

Dihydropyridine calcium channel blocker. Antianginal; antihypertensive

Allgemeine Beschreibung

Nicardipine hydrochloride,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid methyl 2-[methyl(phenylmethyl)amino]ethylester hydrochloride (Cardene), is a more potent vasodilator ofthe systemic, coronary, cerebral, and renal vasculature andhas been used in the treatment of mild, moderate, and severehypertension. The drug is also used in the management of stableangina.

Sicherheitsprofil

Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. Human systemic effects: decreased urine volume or anuria. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx an

2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylatmonohydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylatmonohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	allison@yan-xi.com	China	5857	58
Hebei Weibang Biotechnology Co., Ltd	+8617732866630	bess@weibangbio.com	China	18148	58
airuikechemical co., ltd.	+86-18353166132 +86-18353166132	sales02@airuikechemical.com	China	983	58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.	+86-18600796368 +86-18600796368	sales@sjar-tech.com	China	484	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	8778	55
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29810	58

54527-84-3(2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylatmonohydrochlorid)Verwandte Suche:

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• methyl 2-(benzyl-methyl-amino)ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
• 2-(benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylatemonohydrochloride
• Naratriptan HCl
• 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid Methyl 2-[Methyl(phenylmethyl)amino]ethyl Ester Hydrochloride
• Antagonyl
• Barizin
• Dacarel
• Vasonas
• YC-93
• 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid ethyl ester hydrochloride
• Vasonase
• NICARDIPINE HYDROCHLORIDE (YC-93) CALCIU M CHANNEL ANTAG
• NICARDIPINE HYDROCHLORIDE MM(CRM STANDARD)
• YC-93, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid ethyl ester hydrochloride
• Aprovan
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl 5-[2-[Methyl(phenylMethyl)aMino]ethyl] ester, hydrochloride
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[2-[methyl(phenylmethyl)amino]ethyl] ester, hydrochloride (1:1)
• 5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-2-(
• angioglebil
• benzylmethylamino)ethylmethylester,monohydrochloride
• bionicard
• dafil
• dagan
• lincil
• loxen
• nicardil
• perdipina
• rs-69216
• PERDIPINE
• NICODEL
• NICARDIPINE HCL
• NICARDIPINE HYDROCHLORIDE
• YC-93 HCL
• YC-93 HYDROCHLORIDE
• 1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRIDINE-DICARBOXYLIC ACID 3-METHYL ESTER 5-[2-(METHYL-(BENZYL)AMINO)ETHYL] ESTER HYDROCHLORIDE
• 1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID METHYL 2- [METHYL-(PHENYLMETHYL)AMINO]ETHYL ESTER HYDROCHLORIDE
• 1,4-DIHYDRO-2,6-DIMETHYL-4-[3-NITROPHENYL]METHYL-2-[METHYL(PHENYLMETHYL)AMINO]-3,5-PYRIDINEDICARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE
• Nicardipine Hydrochloride, 99.0+ % (HPLC)
• NicardipineHydrochloride>
• Nicardipine for system suitability
• Nicardipine hydrochloride USP/EP/BP
• 3-(2-(Benzyl(methyl)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
• Antagonil, Dagan, Flusemide)
• Nicardipine HCl (RS69216
• Nicardipine 13CD3 Hydrochloride
• Nicardipine HydrochlorideQ: What is Nicardipine Hydrochloride Q: What is the CAS Number of Nicardipine Hydrochloride Q: What is the storage condition of Nicardipine Hydrochloride Q: What are the applications of Nicardipine Hydrochloride
• Nicardipine Hydrochloride (1463224)
• 13C,2H3]-Nicardipine Hydrochloride
• Nicardipine Hydrochloride, ≥ 98.0%
• 2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylatmonohydrochlorid
• Nicardipine hydrochloride, L-type Ca2+ channel antagonist
• 54527-84-3
• 5427-84-3
• C26H29N3O6HCl
• C26H30ClN3O6
• C25H28ClN3O6
• C26H29N3O6ClH
• Inhibitors and Activators