Rosmarinic acid
|
|
|
- CAS-Nr.
- 20283-92-5
- Englisch Name:
- Rosmarinic acid
- Synonyma:
- ROSMARINATE;Rosmarinic;Labiatic acid;ROSMARINIC ACID(P);ROSMARINIC ACID, HPLC 98%;3-(3,4-DIHYDROXYPHENYL)ACRYLIC ACID-1-CARBOXY-2-(3,4-DIHYDROXYPHENYL)ETHYL ESTER;rosemaryacid;4-dihydroxy-;RosMarinic aci;lemon balm P.E
- CBNumber:
- CB0767565
- Summenformel:
- C18H16O8
- Molgewicht:
- 360.31
- MOL-Datei:
- 20283-92-5.mol
|
Rosmarinic acid Eigenschaften
- Schmelzpunkt:
- 171-175 °C (lit.)
- alpha
- +102～+110°(D/20℃)(c=0.2,C2H5OH)
- Siedepunkt:
- 694.7±55.0 °C(Predicted)
- Dichte
- 1.33
- storage temp.
- 2-8°C
- L?slichkeit
- Soluble in ethanol, DMSO or dimethyl formamide to approximately 25 mg/mL.
- pka
- 2.78±0.10(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to faintly beige
- Biologische Quelle
- Rosemarinus officinalis L.
- Wasserl?slichkeit
- H2O: 1mg/mL, clear, colorless
- BRN
- 2227587
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
- InChI
- InChI=1/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/s3
- InChIKey
- DOUMFZQKYFQNTF-WUTVXBCWSA-N
- SMILES
- C(C1C=CC(O)=C(O)C=1)[C@H](C(=O)O)OC(=O)/C=C/C1C=CC(O)=C(O)C=1 |&1:9,r|
- LogP
- 0.871 (est)
- CAS Datenbank
- 20283-92-5(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T |
|
|
| R-S?tze: |
25 |
|
|
| S-S?tze: |
45 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
GD8990000 |
|
|
| F |
10-23 |
|
|
| HS Code |
29189900 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
|
| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P332+P313 |
Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P337+P313 |
Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
|
Rosmarinic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White to off-white powder
Verwenden
Rosmarinic Acid is a phenolic compound with antioxidant and anti-inflammatory activity. Rosmarinic Acid has been shown to inhibit againts peroxidative damage to biomembranes. Rosmarinic Acid also supp
resses endotoxin-induced activation of complement and concomitant prostacyclin biosynthesis.
Definition
ChEBI: (R)-rosmarinic acid is a stereoisomer of rosmarinic acid having (R)-configuration. It has a role as a plant metabolite and a geroprotector. It is a conjugate acid of a (R)-rosmarinate. It is an enantiomer of a (S)-rosmarinic acid.
Allgemeine Beschreibung
Rosmarinic acid is a bioactive plant phenolic compound with antioxidant and anti-inflammatory effects.
Biologische Aktivit?t
Anti-inflammatory, cytostatic and antiviral.
Mode of action
Rosmarinic acid (RA), a water-soluble polyphenolic compound with antioxidant and anti-inflammatory properties. Inhibits several complement-dependent inflammatory processes via inhibition of the C5 convertase. Anticarcinogenic. Inhibitor of lipid peroxidation, TCR-induced T cell activation and proliferation.?
Rosmarinic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Benzenepropanoic acid, α-[[3-[3,4-bis(2-propenyloxy)phenyl]-1-oxo-2-propenyl]oxy]-3,4-bis(2-propenyloxy)-, 2-propenyl ester, [R-(E)]- (9CI)
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-2-hydroxy-
Benzenepropanoic acid, α-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-, 2-propenyl ester, [R-(E)]- (9CI)
Downstream Produkte
Rosmarinic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 568)Lieferanten
20283-92-5()Verwandte Suche:
- r-(+)-2-(3,4-dihydroxycinnamoyloxy)-3-(3,4-dihydroxyphenyl)propionicacid
- rosemaryacid
- ROSMARINIC ACID 98+% BY HPLC
- RosmarinicAcid10%
- ROSMARINIC ACID(SEE PART# 18370)(SH)
- ROSMARINIC ACID(SH)
- ROSMARINIC ACID WITH HPLC
- Benzenepropanoicacid,α-[[3-(3,4-dihydroxyphen
- yl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-,[R-(E)]-
- (R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester
- (R)-α-[[(E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid
- Rosmarinic acid
- [R-(+)]-α-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoicacid
- Labiatenic acid
- Rosmarinic acid,(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester
- Rosmarinic acid ,95%
- [4ar-(4aa,9b,10a,10ab)]-1,3,4,9,10,10a-hexahydro-5,6,9-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-2h-10,4a-(epoxymethano)phenanthren-12-one
- 3,4-DIHYDROXYCINNAMIC ACID (R)-1-CARBOXY-2-(3,4-DIHYDROXYPHENYL)ETHYL ESTER
- 3,4-dihydroxycinnamicacid2-esterwith3-(3,4-dihydroxyphenyl)lacticacid
- 4-dihydroxy-
- alpha-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-benzenepropanoicaci
- cinnamicacid,3,4-dihydroxy-,2-esterwith3-(3,4-dihydroxyphenyl)lacticacid
- (r)-o-(3,4-dihydroxycinnamoyl)-3-(3,4-dihydroxyphenyl)lactic acid
- (R)-2-(3,4-DIHYDROXYCINNAMOYLOXY)-3-(3,4-DIHYDROXYPHENYL)LACTIC ACID
- (R)-ALPHA-[[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2E-PROPENYL]OXY]-3,4-DIHYDROXY-BENZENEPROPANOIC ACID
- [R-(+)]-ALPHA-[[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL]OXY]-3,4-DIHYDROXYBENZENEPROPANOIC ACID
- (R)-A-[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2E-PROPENYL]OXY-3,4-DIHYDROXYBENZENEPROPANOIC ACID
- Rosmarinic Acid (25 mg)
- Rosmarinic acid, >=98%
- ROSMARINIC ACID FROM ROSMARINUS OFFI
- (R)-rosmarinic acid
- Rosmarinic Acid (>90%)
- RosMarinic acid, froM RosMarinus officinalis
- RosMarinic aci
- Rosmarinic acid
(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4-dihydroxyphenyl)lactic acid
- (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-propanoic acid
- lemon balm P.E
- Rosemary Extract - Rosmarinic Acid
- Rosmarinic acid 20283-92-5
- Rosmarinic acid, 99%, from Rosmarinus officinalis
- Rosmarinic acid, 98%, from Rosmarinus officinalis
- Rosmarinic acid, 99%, from Rosmarinus officinalis L.
- rosmarinic acid powder
- Rosmarinic acid 5-95%
- Rosmarinic acid CRS
- Benzenepropanoic acid,a-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-,(aR)-
- Benzenepropanoic acid, α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-, (αR)-
- (R,E)-3-(3,4-Dihydroxyphenyl)-2-((3-(3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid
- purple perilla extract rosmarinic acid
- Rosemarinic aicd
- 3-(3,4-DIHYDROXYPHENYL)ACRYLIC ACID-1-CARBOXY-2-(3,4-DIHYDROXYPHENYL)ETHYL ESTER
- ROSMARINIC ACID, HPLC 98%
- Rosmarinic
- ROSMARINIC ACID(P)
- ROSMARINATE
- Labiatic acid
- Perilla oil 68132-21-8
- Rosmarinic acid (6CI, 7CI)
