成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

D-Serin

D-Serine Struktur
312-84-5
CAS-Nr.
312-84-5
Bezeichnung:
D-Serin
Englisch Name:
D-Serine
Synonyma:
H-D-SER-OH;(R)-2-amino-3-hydroxypropanoic acid;2-AMINO-3-HYDROXYPROPANOIC ACID;D-Serin;(R)-Serine;β-Hydroxyalanine;DW75;P1010;D-Erine;D-SERINE
CBNumber:
CB0747387
Summenformel:
C3H7NO3
Molgewicht:
105.09
MOL-Datei:
312-84-5.mol

D-Serin Eigenschaften

Schmelzpunkt:
220 °C
Siedepunkt:
197.09°C (rough estimate)
alpha 
-14.75 º (c=10 2 N HCl)
Dichte
1.3895 (rough estimate)
Brechungsindex
1.4368 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
L?slichkeit
H2O: 0.1 g/mL, clear, colorless
pka
2.16±0.10(Predicted)
Aggregatzustand
Crystalline Powder
Farbe
White
Wasserl?slichkeit
346 g/L (20 ºC)
Merck 
14,8460
BRN 
1721403
InChIKey
MTCFGRXMJLQNBG-UWTATZPHSA-N
LogP
-1.490 (est)
CAS Datenbank
312-84-5(CAS DataBase Reference)
EPA chemische Informationen
D-Serine (312-84-5)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 24/25-36-26
WGK Germany  3
RTECS-Nr. VT8200000
TSCA  Yes
HS Code  29225000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

D-Serin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Serine is one of the 20 naturally-occurring amino acids used by all organisms in the biosynthesis of proteins. Having a single chiral center, serine can exist as one of two stereoisomers (L-Serine and D-Serine).
D-serine is categorized as a nootropic. It is an amino acid found in the brain and is produced primarily in astrocytes; the conversion of L-serine to D-serine is catalyzed by the serine racemase enzyme. D-serine acts as a co-agonist of glutamate NMDA receptors and binds at the glycine site. NMDA receptors mediate synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition, and learning. Schizophrenia is characterized by reduced NMDA receptor signaling and therefore, D-serine supplementation has been tested extensively in patients with schizophrenia. It is thought to improve cognitive symptoms in this population. It is worth noting that in Alzheimer’s disease, there is excess glutamate receptor activation. Memantine, one of the drugs used to treat Alzheimer’s disease, is an NMDA receptor antagonist.

Chemische Eigenschaften

D-serine is a off-white crystalline powder with a faint musty odor.It is an amino acid found in the brain. Derived from Glycine, d-serine is a neuromodulator, meaning it regulates the activities of neurons.
D-serine
D-Serine supplementation can reduce symptoms of cognitive decline. It is also able to reduce symptoms of diseases characterized by reduced N-methyl-D-aspartate (NMDA) signaling, which includes cocaine dependence and schizophrenia.

Verwenden

D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate.

Definition

D-serine is the R-enantiomer of serine. It has a role as a NMDA receptor agonist, a human metabolite and an Escherichia coli metabolite. It is a D-alpha-amino acid and a serine. It is a conjugate base of a D-serinium. It is a conjugate acid of a D-serinate. It is an enantiomer of a L-serine. It is a tautomer of a D-serine zwitterion.

Application

D-serine has been used as a substrate in D-amino acid oxidase (DAO) activity in human 1321N1 astrocytoma cells. It has also been used in intracerebroventricular administration in rat for the induction of antinociceptive effect.
D-serine has been used to prevent glycine-dependent desensitization of N-methyl D-aspartate receptor (NMDAR) and to study its effects on NMDARs to correct behavioral abnormalities in rats after partial sciatic nerve ligation (PSNL).

Allgemeine Beschreibung

D-serine is an unusual amino acid expressed in the mammalian brain.

Biologische Aktivit?t

D-serine is an agonist and glycine mimic which is active at the strychnine-insensitive glycine binding site associated with the N-methyl-D-aspartate (NMDA) receptor as well as the inhibitory post-synaptic glycine receptor. Along with glutamate, it has a role in various physiological processes including synaptic plasticity and receptor transmission. Dysregulation of D-serine signaling has been linked with neurodegenerative diseases and disorders.
D-serine is essential for the normal development of dendrites, neuroblast migration and may have therapeutic potential for treating schizophrenia and depression states. The levels of D-serine is elevated in traumatic brain injury (TBI).

D-Serin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


D-Serin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 700)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Apeloa Pharmaceutical Co., Ltd.
+86-0571-87635730 +8615858229168
chem1022@hengdian-group.com China 1478 58
DONBOO AMINO ACID COMPANY
+8613063595538
donboo@donboo.com China 9363 58
Maanshan Tiantai Biotechnology Co., Ltd.
+86-0555-8889890 +86-17356584060
GM@tiantaibio-tech.com China 72 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8806 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810
1022@dideu.com China 3882 58
Hebei Mujin Biotechnology Co.,Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12832 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021
lisa@kingfinertech.com China 3009 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
airuikechemical co., ltd.
+86-18353166132 +86-18353166132
sales02@airuikechemical.com China 983 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+8615350851019
admin@86-ss.com China 1001 58

312-84-5(D-Serin)Verwandte Suche:


  • (R)-2-AMINO-3-HYDROXYPROPIONIC ACID
  • D-SERINE 98.5%
  • D-Serine,>99%
  • D-2-Amino-3-Hydroxypropionic
  • (2R)-2-amino-3-hydroxy-propanoic acid
  • D-Serine, 95+%
  • D-Serine(D-2-AMino-3-hydroxypropanoic acid)
  • Cycloserine Impurity 1 (D-serine)
  • D-Serine Vetec(TM) reagent grade, 99%
  • D-Serine≥ 99% (Titration: anhydrous basis)
  • D-Serine,99%e.e.
  • D-(+)-SERINE
  • D-SERINE
  • D-2-AMINO-3-HYDROXYPROPIONIC ACID
  • D-2-AMINO-3-HYDROXYPROPANOIC ACID
  • D-BETA-HYDROXYALANINE
  • D-SERINE extrapure
  • β-Hydroxyalanine, (R)-2-Amino-3-hydroxypropionic acid, Ser
  • β-Hydroxyalanine, (R)-(-)-Serine, (R)-2-Amino-3-hydroxypropionic acid, 2-Amino-3-hydroxypropanoic acid, Ser
  • Dserine1-norleucine4-valinamide25-β1-25-corticotrophin
  • DW75
  • P1010
  • pentacosactride
  • D-3-Hydroxy-α-alanine
  • D-β-Hydroxyalanine
  • (2R)-2-Amino-3-hydroxypropionic acid
  • (R)-3-Hydroxy-2-aminopropionic acid
  • D-Serine,98%
  • H-D-Ser-OH (D-Serine)
  • D-Serine, 98% 25GR
  • D-Serine, 98% 5GR
  • NSC 77689
  • D-2-Amino-3-hydroxypropionic Acid H-D-Ser-OH
  • Methyl (2R)-3-hydroxy-2-(2,2,2-trifluoroacetaMido)propanoate
  • SERINE, D-(RG)
  • SEROTONIN CREATINE SULFATE(RG)
  • D-2-Aminohydracrylic acid
  • D-Serine, BR
  • D-Erine
  • D-Serine >
  • D-Serine USP/EP/BP
  • (R)-2-AMINO-3
  • dextro-serine
  • β-Hydroxyalanine
  • D-Serin
  • (R)-2-amino-3-hydroxypropanoic acid
  • H-D-SER-OH
  • 2-AMINO-3-HYDROXYPROPANOIC ACID
  • (R)-Serine
  • D-Serine (9CI, ACI)
  • D-Serine, endogenous NMDA receptor co-agonist
  • D-Serine (mM/ml), NMDA receptor co-agonist
  • 312-84-5
  • 312-84-2
  • 321-84-5
  • 3121-84-5
  • C3H7NO3
  • C108H215O31N41S
Copyright 2019 ? ChemicalBook. All rights reserved