9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat)
CAS-Nr.
312-93-6
Bezeichnung:
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat)
Englisch Name:
DEXAMETHASONE SODIUM PHOSPHATE
Synonyma:
EGP437;EGP 437;EGP-437;wymesone;neodecadron;betnelanphosphate;oradexonphosphate;Hexadrol phosphate;examethasonephosphate;dexamethasonephosphate
CBNumber:
CB0500878
Summenformel:
C22H30FO8P
Molgewicht:
472.44
MOL-Datei:
312-93-6.mol
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Eigenschaften
Schmelzpunkt:
154-157°C
Siedepunkt:
669.6±65.0 °C(Predicted)
Dichte
1.45±0.1 g/cm3(Predicted)
storage temp.
-20°C Freezer, Under Inert Atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
1.67±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to Light Brown
Stabilit?t:
Hygroscopic, Moisture Sensitive
Sicherheit
Risiko- und Sicherheitserkl?rung
Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher
Xn
R-S?tze:
62
HS Code
2937220000
Toxizit?t
dni-rat-ipr 3 mg/kg JOENAK 62,527,74
Bildanzeige (GHS)
Alarmwort
Warnung
Gefahrenhinweise
Code
Gefahrenhinweise
Gefahrenklasse
Abteilung
Alarmwort
Symbol
P-Code
H361
Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen.
Reproduktionstoxizit?t
Kategorie 2
Warnung
P201, P202, P281, P308+P313, P405,P501
H373
Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition.
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition)
Kategorie 2
Warnung
P260, P314, P501
Sicherheit
P201
Vor Gebrauch besondere Anweisungen einholen.
P202
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P260
Dampf/Aerosol/Nebel nicht einatmen.
P281
Vorgeschriebene pers?nliche Schutzausrüstung verwenden.
P308+P313
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P314
Bei Unwohlsein ?rztlichen Rat einholen / ?rztliche Hilfe hinzuziehen.
P405
Unter Verschluss aufbewahren.
P501
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
A pro-drug of Dexamethasone (D298800), an anti-inflammatory glucocorticoid. It was found that liposomal DXM-P inhibited both chronic inflammation and joint destruction, whereas free DXM-P failed to prevent joint destruction.
Definition
ChEBI: A steroid phosphate that is the 21-O-phospho derivative of dexamethasone.
Sicherheitsprofil
An experimental teratogen. Otherexperimental reproductive effects. Mutation data reported.When heated to decomposition it emits toxic fumes of F-and POx.
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 93)Lieferanten
Canada 1
China 78
Europe 2
Germany 1
India 6
United Kingdom 1
United States 4
Global 93
312-93-6(9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat))Verwandte Suche:
Desoximetason
Dexamethason-21-(3-phenylpropionat)
Dexamethason-21-pivalat
Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-[(3-sulfobenzoyl)oxy]-, Mononatriumsalz, (11β,16α)-
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17-valerat
9β,11β-Epoxy-17,21-dihydroxy-16α-methylpregna-1,4-dien-3,20-dion
17,21-Dihydroxy-16α-methylpregna-1,4,9(11)-trien-3,20-dion
Dexamethason-21-acetat
9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-21-(hydrogenphosphonat)
Betamethason
17-α,21-Dihydroxy-16-α-methylpregna-1,4,9(11)-trien-3,20-dion-21-acetat
Phosphorsure, Isooctylester
Doxibetasol
Isoflupredon
Hexadecyldihydrogenphosphat
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-(dihydrogenphosphat)
Dexamethason
(11β,16α)-9-Fluoro-11,17-dihydroxy-16-Methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione
Dexamethasone Phosphate (200 mg)K0E2750.996mg/mg(dr)
,21-(dihydrogenphosphate)
betnelanphosphate
[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dihydrogen phosphate
[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] dihydrogen phosphate
[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-3-keto-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] dihydrogen phosphate
Dexamethasone Phosphate (200 mg)
dexamethasone21-orthophosphate
dexamethasonephosphate
neodecadron
oradexonphosphate
wymesone
9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)
Pregna-1,4-Diene-3,20-Dione,9-Fluoro-11,17-Dihydroxy-16-Methyl-21-(Phosphonooxy)-,(11Beta,16Alpha)-
Dexamethasone 21-dihydrogen phosphate
Dexamethasone orthophosphate
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11β,16α)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(dihydrogen phosphate) (8CI)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-phosphate (6CI)
9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)
9-Fluoro-11β,17-dihydroxy-16α-methyl-21-phosphonooxypregna-1,4-diene-3,20-dione
Dexamethasone 21-Phosphate D4Q: What is
Dexamethasone 21-Phosphate D4 Q: What is the CAS Number of
Dexamethasone 21-Phosphate D4 Q: What is the storage condition of
Dexamethasone 21-Phosphate D4 Q: What are the applications of
Dexamethasone 21-Phosphate D4
Dexamethasone Phosphate (1177000)
EGP 437
EGP437
EGP-437
Hexadrol phosphate
9-fluoro-11β,17-dihydroxy-16β-methyl-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate (betamethasone phosphate),
Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, (11b,16a)
examethasonephosphate
1, 4-PREGNADIEN-9α-FLUORO-16α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE 21-PHOSPHATE
9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)
Dexamethasone Hydrogen Phosphate
312-93-6
C22H30FO8P
Drug Analogues
Intermediates & Fine Chemicals
Pharmaceuticals
Steroids
Organics