21-Chlor-9-fluor-17-hydroxy-16β-methylpregna-1,4-dien-3,11,20-trion-17-butyrat
|
|
- CAS-Nr.
- 25122-57-0
- Bezeichnung:
- 21-Chlor-9-fluor-17-hydroxy-16β-methylpregna-1,4-dien-3,11,20-trion-17-butyrat
- Englisch Name:
- Clobetasone butyrate
- Synonyma:
- eumovate;Clobetasone-17-butyrate;sn203;Emovate;CCl 5537;molivate;GR 2/1214;Kindavate;(16-beta)-);17-Butyrate
- CBNumber:
- CB0497976
- Summenformel:
- C26H32ClFO5
- Molgewicht:
- 478.98
- MOL-Datei:
- 25122-57-0.mol
|
21-Chlor-9-fluor-17-hydroxy-16β-methylpregna-1,4-dien-3,11,20-trion-17-butyrat Eigenschaften
- Schmelzpunkt:
- 90-100°
- Siedepunkt:
- 573.3±50.0 °C(Predicted)
- Dichte
- 1.1736 (estimate)
- storage temp.
- Refrigerator, Under Inert Atmosphere
- L?slichkeit
- Practically insoluble in water, freely soluble in acetone and in methylene chloride, slightly soluble in ethanol (96 per cent).
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilit?t:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChIKey
- FBRAWBYQGRLCEK-JGSYYNBSNA-N
- SMILES
- [C@]1(C(=O)CCl)(OC(=O)CCC)[C@@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C |&1:0,11,14,16,26,28,33,r|
- CAS Datenbank
- 25122-57-0(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher |
Xn |
|
|
R-S?tze: |
40 |
|
|
S-S?tze: |
22-36 |
|
|
WGK Germany |
3 |
|
|
RTECS-Nr. |
TU4154083 |
|
|
HS Code |
29372290 |
|
|
Toxizit?t |
mouse,LD50,intraperitoneal,500mg/kg (500mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 838, 1983. |
|
|
Bildanzeige (GHS) |
|
Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H351 |
Kann vermutlich Krebs verursachen. |
Karzinogenit?t |
Kategorie 2 |
Warnung |
|
P201, P202, P281, P308+P313, P405,P501 |
|
Sicherheit |
P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
|
21-Chlor-9-fluor-17-hydroxy-16β-methylpregna-1,4-dien-3,11,20-trion-17-butyrat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R40:Verdacht auf krebserzeugende Wirkung.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White or almost white powder.
Verwenden
Clobetasone butyrate is a synthetic glucocorticoid which is used as an anti-inflammatory in the treatment of various skin disorders. As a steroid medicine, it can used on the skin to treat swelling, itching and irritation. Such as eczema, including ;contact dermatitis; psoriasis; insect bites and stings; nappy rash.
21-Chlor-9-fluor-17-hydroxy-16β-methylpregna-1,4-dien-3,11,20-trion-17-butyrat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
21-Chlor-9-fluor-17-hydroxy-16β-methylpregna-1,4-dien-3,11,20-trion-17-butyrat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 176)Lieferanten
25122-57-0(21-Chlor-9-fluor-17-hydroxy-16β-methylpregna-1,4-dien-3,11,20-trion-17-butyrat)Verwandte Suche:
- (16-beta)-)
- 11,20-trione,21-chloro-9-fluoro-17-hydroxy-16-beta-methyl-pregna-4-diene-3
- 21-chloro-9-fluoro-17-hydroxy-16-beta-methylpregna-1,4-diene,3,11,20-trione
- molivate
- pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy
- sn203
- 21-chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione 17-butyrate
- ClobetasolPropionate-Bp/Ep/Usp
- Butyric acid, ester with 21-chloro-9-fluoro-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione (8CI)
- CCl 5537
- Emovate
- GR 2/1214
- Kindavate
- Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16β)-
- Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16β-methyl-, butyrate (8CI)
- 21-Chloro-9-fluoro-17-hydroxy-16b-methylpregna-1,4-diene-3,11,20-trione 17-butyrate
- Clobetasone butyrate
- CLOBETASOLE BUTYRATE
- 21-Chloro-9-fluoro-16β-methyl-17-(1-oxobutoxy)pregna-1,4-diene-3,11,20-trione
- 21-Chloro-9-fluoro-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione=butyrate
- [(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate
- [(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroethanoyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate
- butyric acid [(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-3,11-diketo-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] ester
- 17-Butyrate
- )-pregn-5-en-20-one
- 3,17-Dihydroxy-16-methyl-(3&beta
- )-3,17-Dihydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methyl|piperidinium Bromide
- )-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
- )-3-(Acetyloxy)-17-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide-d3
- -Hydroxytestosterone
- )-11-Hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-pregna-1,4-diene-3,20-dione
- )-17-Acetyloxy-3-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide
- )-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4,9(11)-triene-3,20-dione
- 20R)-9-Fluoro-11,20-dihydroxy-16-methyl-3-oxopregna-1,4-dien-21-oic Acid|(Betamethasone Impurity)
- )-3-(Acetyloxy)-17-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide
- -Hydroxy Stanozolol
- H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione|(Deflazacort Impurity)
- )-9-Fluoro-11,17,21-trihydroxy-16-methylpregn-4-ene-3,20-dione
- )-17,21-Bis(acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione
- -Hydroxy-17-epi-norethisterone
- H-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione
- -Hydroxymestanolone
- )-6-Bromo-9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxopentyl)oxy]-pregna-1,4-diene-3,20-dione
- Clonazepam impurity B CRS
- Clobetasone butyrate for system suitability CRS
- Clobetasone butyrate CRS
- Clobetasone butyrate solution in Acetonitrile,100μg/mL
- Clobetasone ButyrateQ: What is
Clobetasone Butyrate Q: What is the CAS Number of
Clobetasone Butyrate Q: What is the storage condition of
Clobetasone Butyrate
- 4-(methylamino)-3-nitro-
- eumovate
- Clobetasone-17-butyrate
- 21-chloro-9-fluoro-16β-methyl-3,11,20-trioxopregna-1,4-dien-17-ylbutanoate
- Betamethasone Butyrate/Clobetamethasone Butyrate
- Simvastatin Impurity 44
- 25122-57-0
- C26H32ClFO5
- Intermediates & Fine Chemicals
- Pharmaceuticals