5-Amino-3-oxopentansaeure
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- CAS-Nr.
- 5451-09-2
- Bezeichnung:
- 5-Amino-3-oxopentansaeure
- Englisch Name:
- 5-Aminolevulinic acid hydrochloride
- Synonyma:
- 5-Ala;5-AMINOLEVULINIC ACID HCL;5-Aminolevulinic;inic acid hydrochL;5-AMINO-4-OXOPENTANOIC ACID HYDROCHLORIDE;evuL;Gliolan;5-AminoL;DELTA-AMINOLEVULINIC ACID HYDROCHLORIDE;ALA-PDT
- CBNumber:
- CB0496757
- Summenformel:
- C5H10ClNO3
- Molgewicht:
- 167.59
- MOL-Datei:
- 5451-09-2.mol
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5-Amino-3-oxopentansaeure Eigenschaften
- Schmelzpunkt:
- ~150 °C (dec.)
- chüttdichte
- 400kg/m3
- Flammpunkt:
- 155-157°C
- storage temp.
- -20°C
- L?slichkeit
- H2O: 50 mg/mL
- Aggregatzustand
- powder
- Farbe
- White to pale yellow
- PH
- pH (10g/l, 25℃) : 2.5～3.0
- Wasserl?slichkeit
- Soluble in dimethyl sulfoxide, methanol and water.
- Decomposition
- 155-157 ºC
- Sensitive
- Hygroscopic
- Merck
- 14,446
- BRN
- 3690651
- Stabilit?t:
- Hygroscopic
- InChIKey
- ZLHFONARZHCSET-UHFFFAOYSA-N
- CAS Datenbank
- 5451-09-2(CAS DataBase Reference)
5-Amino-3-oxopentansaeure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R66:Wiederholter Kontakt kann zu spr?der oder rissiger Haut führen.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white to pale yellow crystals or
Verwenden
5-Aminolevulinic acid hydrochloride finds an important role as a precursor in the synthesis of tetrapyrroles such as chlorophyll and heme. It is widely utilized in photodynamic therapy of diseases namely, Paget?s disease and human papillomavirus (HPV) infection-associated cervical condylomata acuminata.
Application
5-Aminolevulinic acid hydrochloride has been used to activate or inhibit heme biosynthesis in HeLa and K562 cell lines. It has also been used in photodynamic therapy in mice with A431 tumours. Clinical oral administration of 5-Aminolevulinic acid hydrochloride potentiates the antihypertensive effects associated with anaesthetics and is used in the treatment of hypertensive patients, particularly in elderly hypertensive patients receiving antihypertensive medications
[1-2].
Definition
ChEBI: 5-aminolevulinic acid hydrochloride is a hydrochloride that is the monohydrochloride of 5-aminolevulinic acid. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. It has a role as an antineoplastic agent, a photosensitizing agent, a dermatologic drug and a prodrug. It contains a 5-ammoniolevulinic acid.
l?uterung methode
Dry ALA-HCl in a vacuum desiccator over P2O5 overnight, then crystallise it by dissolving it in cold EtOH and adding dry Et2O. Also crystallis
5-Amino-3-oxopentansaeure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-Amino-3-oxopentansaeure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 605)Lieferanten
5451-09-2(5-Amino-3-oxopentansaeure)Verwandte Suche:
- TIMTEC-BB SBB003880
- DELTA-AMINOLEVULINIC ACID HYDROCHLORIDE CELL CULTUR
- 5-AminolevulinicAcidHydrochloride(5-Ala)
- 5-Aminolevulinicacidhydrochloride,99%
- 5-Aminolevulinatehydrochloride
- 5-amino-levulinicacihydrochloride(8ci)
- Levulinicacid,5-amino-,hydrochloride(8Cl)
- 5-amino-3-oxopentanoic acid
- 5-Aminolevulinic-3-13C Acid HCl
- 5-Aminolevulinic acid hydrochloride,δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA
- 5-Aminolevulinic acid hydrochloride, 5-Amino-4-oxovaleric acid hydrochloride
- 5-AMinolevulinic acid hydrochloride, 99% 500MG
- 5-AMinolevulinic Acid HCl (5-ALA HCl)
- Pentanoicacid, 5-aMino-4-oxo-, hydrochloride (1:1)
- 5-Aminolevulinic acid/ALT
- ALA-PDT
- Aminolevulinic acid hydrochloride (USAN)
- Levulan (TN)
- Levulan Kerastick
- Levulinic acid, 5-amino-, hydrochloride
- Levulinic acid, 5-amino-, hydrochloride (8CI)
- Pentanoic acid, 5-am
- 5-amino-4-oxo-pentanoic acid, hydrochloride (1:1)
- 5-Amino-3-oxopentanoic acid (hydrochloride)
- 5ALA,5-Aminolevulinic acid hydrochloride
- δ-Aminolevulinic acid hydrochloride≥ 99% (Assay)
- ALA HCL
- ALA HYDROCHLORIDE
- GAMMA-AMINOLEVULINIC ACID HYDROCHLORIDE
- D-AMINOLEVULINIC ACID HCL
- DELTA-ALA, HCL
- DELTA-AMINOLEVULINIC ACID HCL
- 5-Aminolevulinic Acid-4-13CHCI
- 5-Aminolevulinic Acid-5-13CHCI
- Pentanoic acid, 5-amino-4-oxo-, hydrochloride
- δ-aminolevulinic acid hydrochloride
- 5-AMINO-4-OXOPENTANOICACIDHYDROCHLORIDE(5-AMINOLEVULINICACIDHYDROCHLORIDE)
- 5-Amino-4-oxopentanoic acid hydrochloride 98%
- 5-Aminolevulinic acid hydrochloride, 5-Amino-4-ketovaleric acid hydrochloride
- 5-AMINOLEVULINIC ACID HYDROCHLORIDE 98+%
- ä-Aminolevulinic acid hydrochloride
- δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA
- 5-Aminolevulinic Acid-5-13CCI
- 5-Aminolevulinic Acid-4-13CCI
- 4-Carboxy-2-oxobutylamine·hydrochloride
- 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA
- 5-AMINOLAEVULINIC ACID HYDROCHLORIDE
- 5-AMINOLEVULINIC ACID HYDROCHLORIDE
- 5-amino-4-ketovaleric acid hydrochloride
- 5-AMINO-4-OXOPENTANOIC ACID HCL
- 5-Aminolevulinic Acid Hydrochloride >
- 5-aminoacetoylacetate
- 5-Aminolevulinic Acid Hydrochlorid
- 5-Aminolevulinic acid hydrochloride USP/EP/BP
- 5-Amino-3-oxopentansaeure
- 5-aminolevulinic acid hcl,5-ALA
- Aminolevulinic acid HCl (ALA)
- 5-Aminolevulinic Acid-13C2,15N HCl
