3-Aminophenylborsaeure hemisulfat
|
|
|
- CAS-Nr.
- 66472-86-4
- Bezeichnung:
- 3-Aminophenylborsaeure hemisulfat
- Englisch Name:
- 3-Aminobenzeneboronic acid hemisulfate salt
- Synonyma:
- 3-AMINOPHENYLBORONIC ACID HEMISULFATE;M-APBA;SKL266;3-Aminobenzeneboroni;boronic acid hemisuL;M-AMINOPHENYLBORIC ACID HEMISULFATE;(3-aminophenyl)-boronic aci sulfate;aminophenylboronic acid hemisulfate;3-aminophenylboric acid hemisulphate;M-AMINOPHENYLBORONIC ACID HEMISULFATE
- CBNumber:
- CB0357728
- Summenformel:
- C12H18B2N2O8S
- Molgewicht:
- 371.96692
- MOL-Datei:
- 66472-86-4.mol
|
3-Aminophenylborsaeure hemisulfat Eigenschaften
- Schmelzpunkt:
- ≥300 °C
- storage temp.
- Inert atmosphere,2-8°C
- Wasserl?slichkeit
- Soluble in water
- Aggregatzustand
- Crystalline Powder
- Farbe
- White to slightly beige
- Sensitive
- Hygroscopic
- BRN
- 8094151
- InChIKey
- XMVGYYBQCXVVHU-UHFFFAOYSA-N
- CAS Datenbank
- 66472-86-4
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
|
|
| R-S?tze: |
36/37/38 |
|
|
| S-S?tze: |
26-36-37/39 |
|
|
| WGK Germany |
3 |
|
|
| F |
3-10 |
|
|
| HazardClass |
IRRITANT |
|
|
| HS Code |
29310095 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
|
| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P332+P313 |
Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P337+P313 |
Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
|
3-Aminophenylborsaeure hemisulfat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
White to slightly beige crystalline powder
Verwenden
3-Aminobenzeneboronic acid hemisulfate salt is a boronic acid derivative, which can be used as an intermediate in pharmaceutical synthesis. Adsorbent additive for the chromatographic separation of 3'-terminal polynucleotides from RNA.
Application
3-Aminophenylboronic acid hemisulfate salt is used in the synthesis of:
Phenylboronic acid-functionalized inverse opal hydrogels within microfluidic flow cells for glucose sensing.
Phenylboronic acid-salicylhydroxamic acid-derived complexing reagent for protein immobilization on chromatographic support.
It can also be used in the preparation of phenylboronic acid (PBA) monolayer-modified Au electrode for the voltammetric sensing of uridine and cytidine.
synthetische
3-Aminobenzeneboronic acid hemisulfate salt synthesis: Benzenamine, 3-bromo-N-(diphenylmethylene)- (80,0 g; 0.24 moles) was added to the cryogenic reactor along with 1.4 equivalents of triisopropyl borate and dissolved in tetrahydrofuran. The resulting solution was cooled to -80°C under an inert atmosphere and 1.35 equivalents of n-butyllithium (as a solution in n-hexane) was added maintaining the internal temperature. When complete conversion was achieved, the reaction mixture was added to a dilute mixture of sulfuric acid (1 M) and toluene. The layers were separated to obtain an aqueous solution of 3-aminophenylboronic acid hydrogen sulfate (assay yield: 85%). 3-Aminobenzeneboronic acid hemisulfate salt can be obtained by precipitating a 0.5 M aqueous solution at pH 7.2 (pH corrected with 33% aqueous NaOH) at a temperature of 0-5°C. Filtration and drying under vacuum at 40°C for 8 hours yielded 21.7 g of 3-Aminobenzeneboronic acid hemisulfate salt (0.16 moles; 66% molar yield).
3-Aminophenylborsaeure hemisulfat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-Aminophenylborsaeure hemisulfat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 214)Lieferanten
66472-86-4(3-Aminophenylborsaeure hemisulfat)Verwandte Suche:
- M-AMINOPHENYLBORONIC ACID HEMISULFATE
- M-AMINOPHENYLBORONIC ACID HEMISULFATE SALT
- M-AMINOPHENYL BORONIC ACID, HEMISULPHATE
- M-AMINOPHENYLBORIC ACID HEMISULFATE
- M-APBA
- (3-aminophenyl)-boronicacisulfate(2:1)
- 3-aminophenylboric acid hemisulphate
- 3-Aminophenylboronic acid hemisulfate salt, >=95%
- M-AMINOPHENYLBORONIC ACIDHEMI-HYDROGEN S ULFATE
- 3-Aminobenzeneboronic acid hemisulfate, 98+%
- Boronic acid, (3-aminophenyl)-, sulfate (2:1)
- 3-aminophenylboronic acid hemisulfate salt
- (3-aminophenyl)-boronic aci sulfate
- aminophenylboronic acid hemisulfate
- 3-AMINOPHENYLBORONIC ACID 0.5 SULFATE
- 3-Aminobenzeneboronic acid hemisulphate, 98+%
- 3-AMINOBENZENEBORONIC ACID HEMISULFATE
- 3-AMINOBENZENEBORONIC ACID HEMISULFATE SALT
- 3-AMINOBENZENEBORONIC ACID HEMISULPHATE
- (3-AMINOPHENYL)BORONIC ACID HEMISULPHATE
- (3-Aminophenyl)boric acid hemisulfate
- (3-Aminophenyl)boronic acid·1/2sulfuric acid
- 3-Aminophenylboronic acid hemisulfate,98%
- p-Aminobenzeneboronic acid hemisulfate
- 3-Aminophenylboronic acid hemisulfate salt ,98%
- 3-Aminobenzeneboroni
- 3-AMinophenylboronic acid heMisulfate, 98% 1GR
- (3-AMinophenyl)boronic acid sulfate (2:1)
- Bis[3-dihydroxyboranyl)benzenaminium] sulfate
- 3-Aminophenylboric acid sulphate(2:1)
- 3-Aminobenzeneboronic acid hemisulfate for synthesis
- 3-Aminophenylboronic Acid Hemisulfate >
- boronic acid hemisuL
- 3-Aminobenzeneboronicacidhemisulfatesal
- SKL266
- 3-AMINOPHENYLBORONIC ACID HEMISULFATE
- 66472-86-4
- C12H18B2N2O8S
- C6H8BNO212H2O4S
- H2NC6H4BOH205H2SO4
- C6H8BNO212H2SO4
- C6H8BNO2x05H2SO4
- C6H8BNO2H2O4S
- 2C6H8BNO2H2O4S
- C6H8BNO205H2SO4
- C6H8BNO205H2O4S
- 2C6H8BNO2H2SO4
- C6H8BNO2sup1sup2H2SO4
- C6H10BNO6S
- BORONIC ACID
- Boronic Acids
- B (Classes of Boron Compounds)
- Boronic Acids and Derivatives
- Aryl
- Organometallic Reagents
- B (Classes of Boron Compounds)
- Boronic Acids
- Boronic acid
