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2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE

2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE Struktur
71119-11-4
CAS-Nr.
71119-11-4
Englisch Name:
2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE
Synonyma:
Bucindolol;Bucindololum;Unii-E9uo06K7ce;Bucindololum [inn-latin];3-[2-[3-(o-Cyanophenoxy)-2-hydroxypropylamino]-2-methylpropyl]-1H-indole;2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE;2-(2-hydroxy-3-((2-(1h-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)benzonitr;2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile;Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)-
CBNumber:
CB0263148
Summenformel:
C22H25N3O2
Molgewicht:
363.45
MOL-Datei:
71119-11-4.mol

2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE Eigenschaften

Schmelzpunkt:
125-127°
Siedepunkt:
605.3±55.0 °C(Predicted)
Dichte
1.21±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
13.76±0.20(Predicted)
Farbe
White to Off-White
Stabilit?t:
Hygroscopic

Sicherheit

2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Antihypertensive.

Biologische Aktivit?t

Non-selective β -adrenoceptor antagonist with additional α 1 -adrenoceptor blocking activity. K i values are 1.61, 1.20 and 68.9 nM for β 1 -, β 2 - and α 1 -adrenoceptors respectively. Also acts as a weak 5-HT 2A/2B antagonist. Displays vasodilatory and antihypertensive actions.

2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 45)Lieferanten
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71119-11-4()Verwandte Suche:

  • 2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE
  • 2-(2-hydroxy-3-((2-(1h-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)benzonitr
  • Bucindolol
  • 2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile
  • 3-[2-[3-(o-Cyanophenoxy)-2-hydroxypropylamino]-2-methylpropyl]-1H-indole
  • Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)-
  • Bucindololum
  • Bucindololum [inn-latin]
  • Unii-E9uo06K7ce
  • 71119-11-4
  • C22H25N3O2
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