5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinhydrobromid
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- CAS-Nr.
- 1944-12-3
- Bezeichnung:
- 5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinhydrobromid
- Englisch Name:
- FENOTEROL HYDROBROMIDE
- Synonyma:
- Airum;Emitex;Ugacor;berotec;th1165a;Siobetec;Dosberotec;partusisten;FENOTEROL HBR;fenoterolbromide
- CBNumber:
- CB0210728
- Summenformel:
- C17H21NO4.BrH
- Molgewicht:
- 384.27
- MOL-Datei:
- 1944-12-3.mol
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5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinhydrobromid Eigenschaften
- Schmelzpunkt:
- 226-228°C
- storage temp.
- 2-8°C
- L?slichkeit
- Soluble in water and in ethanol (96 per cent).
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| S-S?tze: |
36 |
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| RIDADR |
3249 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
DO1500000 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| HS Code |
29225090 |
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| Toxizit?t |
LD50 in mice (mg/kg): 1100 s.c.; 1990 orally (Goldenthal) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinhydrobromid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White Solid
Verwenden
An β2-adrenergic agonist. Bronchodilator; tocolytic.
Definition
ChEBI: The hydrobromide salt of fenoterol. A beta2-adrenergic agonist, it is used as a bronchodilator in the management of reversible airway obstruction.
Clinical Use
Fenoterol is an investigational drug in the United States that has been in use in Europe since
1970. It is the p-hydroxyphenyl derivative of metaproteronol, and the combination of the
resorcinol ring and the bulky p-hydroxyphenyl isopropyl group on the nitrogen gives fenoterol
significant β2-receptor selectivity. It has approximately half the affinity for the β2-receptor as
compared to albuterol. The resorcinol ring is resistant to COMT metabolism, and the bulky
nitrogen substituent greatly retards MOA metabolism as well giving fenoterol a reasonable oral
bioavailability with pharmacokinetics similar to albuterol (i.e., rapid onset and a 4- to 6-hour
duration of action after oral inhalation).
5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinhydrobromid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinhydrobromid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 121)Lieferanten
1944-12-3(5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinhydrobromid)Verwandte Suche:
- FENOTEROL HBR
- FENOTEROL HYDROBROMIDE
- 2-[3,5-DIHYDROXYPHENYL]-2-HYDROXY-2'-[4-HYDROXYPHENYL]-1'-METHYLDIETHYLAMINE HYDROBROMIDE
- 1-(3,5-dihydroxy-phenyl)-2-((1-(4-hydroxybenzyl)ethyl)amino)-ethanolhydrobro
- berotec
- berotechydrobromide
- fenoterolbromide
- partusisten
- phenoterolhydrobromide
- th1165a
- 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]resorcinol hydrobromide
- Fenoterolhydrobromid
- 1-(3,5-Dihydroxyphenyl)-2-[2-(3-p-hydroxyphenyl)propylamino]ethanol hydrobromide
- 1-(p-Hydroxyphenyl)-2-(β-3',5'-dihydroxyphenyl-β-hydroxy)ethylaminopropane hydrobromide
- 1,3-Benzenediol, 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-, hydrobromide
- 3,5-Dihydroxy-α-[(p-hydroxy-α-methylphenethyl)amino]methylbenzyl alcohol hydrobromide
- 3,5-Dihydroxy-α-[[(p-hydroxy-α-methylphenethyl)amino]methyl]benzyl alc. monohydrobromide
- Airum
- Benzyl alcohol, 3,5-dihydroxy-α-[[(p-hydroxy-α-methylphenethyl)amino]methyl]-, hydrobromide (8CI)
- Dosberotec
- 5-[1-hydroxy-2-[1-(4-hydroxyphenyl)propan-2-ylamino]ethyl]benzene-1,3-diol hydrobromide
- Emitex
- Siobetec
- Ugacor
- FenoteroleHydrobromide
- 5-[1-Hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-1,3-benzenediol hydrobromide
- Fenoterol hydrobromide,2-(3,5-Dihydroxyphenyl)-2-hydroxy-2′-(4-hydroxyphenyl)-1′-methyldiethylamine hydrobromide
- Fenoterol solution
- Fenoterol HydrobroMide USP
- 1,3-Benzenediol,5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-Methylethyl]aMino]ethyl]-, hydrobroMide(1:1)
- Fenoterol hydrobromide CRS
- Fenoterol for peak identification CRS
- Fenoterol HBr (Mixture of Diastereomers)
- Fenoterol in Methanol
- FENOTEROL HYDROBROMIDE USP/EP/BP
- Fenoterol hydrobromide 100 μg/ml Acetonitrile
- XA13497000ALFenoteroLhydrobromidE100μg/mLin
- C13497000 FenoteroLhydrobromide
- Fenoterol hydrobromide in Acetonitrile
- 1944-12-3
- C17H22BrNO4
- beta2-adrenoceptor agonist; bronchodilator.
- Amines
- Aromatics
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Adrenoceptor
