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87530-30-1

中文名稱 4,7-二羥基-2-甲氧基-9,10-二氫菲
英文名稱 7-Methoxy-9,10-dihydrophenanthrene-2,5-diol
CAS 87530-30-1
分子式 C15H14O3
分子量 242.27
MOL 文件 87530-30-1.mol
更新日期 2025/05/26 21:01:27
87530-30-1 結(jié)構(gòu)式 87530-30-1 結(jié)構(gòu)式

基本信息

中文別名
4,7-二羥基-2-甲氧基-9,10-二氫菲
英文別名
Lusianthridin
9,10-Dihydro-2-methoxyphenanthrene-4,7-diol
7-Methoxy-9,10-dihydrophenanthrene-2,5-diol
2,5-Phenanthrenediol, 9,10-dihydro-7-methoxy-
4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene
所屬類別
化學(xué)試劑:多環(huán)化合物

物理化學(xué)性質(zhì)

沸點(diǎn)507.3±50.0 °C(Predicted)
密度1.296±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
酸度系數(shù)(pKa)9.23±0.20(Predicted)
形態(tài)粉末
顏色White to off-white
4,7-二羥基-2-甲氧基-9,10-二氫菲價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2025/05/22HY-1214184,7-二羥基-2-甲氧基-9,10-二氫菲
Lusianthridin
87530-30-11 mg3200元
2023/03/20HY-1214184,7-二羥基-2-甲氧基-9,10-二氫菲
Lusianthridin
87530-30-15mg11500元
2023/03/20HY-1214184,7-二羥基-2-甲氧基-9,10-二氫菲
Lusianthridin
87530-30-110mg18500元

常見(jiàn)問(wèn)題列表

生物活性
Lusianthridin 是來(lái)自 Dendrobium venustum 的天然化合物,具有抗遷移作用。Lusianthridin 通過(guò)抑制Src-STAT3 信號(hào),促進(jìn)c-Myc 的降解。
體外研究

Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells.
Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively.

Cell Viability Assay

Cell Line: The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells [1] . 0-100 μM.
Concentration: 0-100 μM.
Incubation Time: 24 h.
Result: Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells.
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