6068-78-6
中文名稱
3,3',4'-三羥基黃酮
英文名稱
2',3'-DIMETHOXY-3-HYDROXYFLAVONE
CAS
6068-78-6
分子式
C15H10O5
分子量
270.24
MOL 文件
6068-78-6.mol
6068-78-6 結(jié)構(gòu)式
基本信息
中文別名
3,3',4'-三羥基黃酮 英文別名
DiOHF5,7-Dideoxyquercetin
3',4'-DIHYDROXYFLAVONOL
2',3'-DIMETHOXYFLAVONOL
3,3',4'-TRIHYDROXYFLAVONE
2',3'-DIMETHOXY-3-HYDROXYFLAVONE
3, 3′, 4′-Trihydroxyflavone, DiOHF
3',4'-Dihydroxyflavonol >=98% (HPLC)
2-(3,4-Dihydroxyphenyl)-3-hydroxy-4H-chromen-4-one
2-(3,4-Dihydroxyphenyl)-3-hydroxy-4H-benzopyran-4-one
所屬類(lèi)別
有機(jī)原料：酮類(lèi)化合物物理化學(xué)性質(zhì)
熔點(diǎn)301-303 °C (decomp)(Solv: methanol (67-56-1))
沸點(diǎn)508.9±50.0 °C(Predicted)
密度1.579±0.06 g/cm3(Predicted)
儲(chǔ)存條件2-8°C
溶解度二甲基亞砜：>15mg/mL
酸度系數(shù)(pKa)8.58±0.20(Predicted)
形態(tài)粉末
顏色淡黃色至深黃色
常見(jiàn)問(wèn)題列表
生物活性
3',4'-Dihydroxyflavonol (DiOHF) 是一種有效的抗氧化劑，可降低糖尿病大鼠腸系膜動(dòng)脈中的超氧化物并改善 NO 功能。體外研究
3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function.
3',4'-Dihydroxyflavonol reduces vascular contraction through Ca
2?
desensitization in permeabilized third-order branches of rat mesenteric arteries.