56092-81-0
基本信息
離子霉素(乙醇溶液)
IONOMYCIN游離態(tài)
離子霉素, 來源于鏈霉菌
來自共生鏈霉菌的IONOMYCIN
羅紅霉素(游離酸)(鏈霉菌屬載體)
SQ-23377
IONOMYCIN
SQ 23377, EM 94
Ionomycinefreeacid
IONOMYCIN (SQ23377)
IONOMYCIN USP/EP/BP
Ionomycin Free Acid (85%)
IONOMYCIN, STREPTOMYCES CONGLOBATUS
Ionomycin from Streptomyces conglobatus
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
報(bào)價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
2024/11/08 | HY-13434 | 離子霉素 Ionomycin | 56092-81-0 | 1mg(14.1mM * 100μL in Ethanol) | 1450元 |
2024/11/08 | HY-13434 | 離子霉素 Ionomycin | 56092-81-0 | 5mg(14.1mM * 500μL in Ethanol) | 3900元 |
2024/08/19 | HY-13434 | 離子霉素 Ionomycin | 56092-81-0 | 10 mg (14.1 mM * 1 mL in Ethanol) | 6300元 |
常見問題列表
Calcium ionophore
Ionomycin is a Calcium ionophore and an antibiotic produced by
Streptomyces conglobatus
.
Addition of 2 μM Ionomycin to LCLC 103H cells causes an instantaneous increase in intracellular Ca
2+
concentration from 50 to 180 nM. DNA and protein analysis in Ionomycin-treated cultures revealed DNA fragmentation and PARP cleavage to an 85-kDa fragment typical of caspase-mediated apoptosis. Necrosis could be detected in ~1-5% of the Ionomycin treated cells. Caspase activation in whole cells was followed by monitoring the increase in activity against Ac-DEVD-amc following Ionomycin treatment.
Ionomycin-mediated cleavage and exosome release. Following Ionomycin exposure, medium conditioned by SKOV3ip cells had increased amounts of exosomes containing the L1-32 cleavage fragment.