34080-08-5
34080-08-5 結(jié)構(gòu)式
基本信息
(S型)原人參三醇
20(S)-原人參三醇
20(S)-原人參三醇(PPT)
20 (S)-原人參三醇, >98%
原人參三醇10MM*1ML (IN DMSO)
原人參三醇10MM*1ML (IN DMSO)標(biāo)準(zhǔn)品
20(S)-APPT
PROTOPANAXTRIOL
S-Protopanaxatriol
PROTOPANAXADIOL(RG)
Protopanaxtriol ,98%
20(S)-Protopanaxtriol
(2S)-Protopanaxatriol
Protopanaxatriol, 20S-
20(S)-Protopanaxtriol(PPT)
物理化學(xué)性質(zhì)
應(yīng)用領(lǐng)域
藥理藥效:原人參三醇型皂苷可以體外協(xié)同抗原負(fù)載誘導(dǎo)小鼠骨髓細(xì)胞的樹突狀細(xì)胞成熟，發(fā)揮對腫瘤細(xì)胞的特異細(xì)胞毒作用；其次，PPT型皂苷注射液能明顯改善大腦中動脈阻塞(MCAO)大鼠的偏癱體征、縮小腦內(nèi)梗死面積、緩解腦水腫癥狀。
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | S3617 | 20(s)-原人參三醇 (20S)-Protopanaxatriol | 34080-08-5 | 5mg | 794.62元 |
| 2024/11/08 | S3617 | 20(s)-原人參三醇 (20S)-Protopanaxatriol | 34080-08-5 | 25mg | 2023.18元 |
| 2023/03/20 | XW340808502 | 20 (S)-原人參三醇 | 34080-08-5 | 100MG | 2669元 |
常見問題列表
Glucocorticoid receptor, Oestrogen receptor, LXRα
(20S)-Protopanaxatriol works through the glucocorticoid receptor (GR) and oestrogen receptor (ER) in human umbilical vein endothelial cells (HUVECs). (20S)-Protopanaxatriol (g-PPT) increases [Ca 2+ ] i with an EC 50 of 482 nM in HUVECs. (20S)-Protopanaxatriol (1 μM) elevates NO production via ERβ. (20S)-Protopanaxatriol (PPT) inhibits the autonomous transactivation of Gal4-LXRα LBD, the T0901317-dependent transcription of SREBP-1c and its promoter. (20S)-Protopanaxatriol (10 μg/mL) blocks the recruitment of RNA polymerase II to the LXRE region of SREBP-1c. (20S)-Protopanaxatriol also inhibits T0901317-dependent transcription of LXRα target genes related to lipogenesis, and reduces T0901317-induced cellular triglyceride (TG) accumulation in primary hepatocytes, but does not alter transcription of ABCA1, also an LXRα target gene.