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1708118-13-1

中文名稱 依維莫司雜質012-99
英文名稱 Everolimus Ring-Opening Impurity
CAS 1708118-13-1
分子式 C53H83NO14
分子量 958.224
MOL 文件 1708118-13-1.mol
更新日期 2024/12/10 09:01:51
1708118-13-1 結構式 1708118-13-1 結構式

基本信息

中文別名
依維莫司雜質29
依維莫司雜質012-99
依維莫司雜質2(012-99)
英文別名
Everolimus Impurity 33
Everolimus Impurity 012-99
Everolimus Open-Ring Impurity
Everolimus Impurity 2(012-99)
Everolimus Open-Ring Aldehyde Impurity
EverolimusRetroaldolDegradationProduct
(S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)
(S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate
(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl (S)-1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate

物理化學性質

熔點45-50°C
儲存條件Amber Vial, -86°C Freezer, Under inert atmosphere
溶解度可溶于氯仿(少許)、甲醇(少許)
形態(tài)固體
顏色白色至灰白色
穩(wěn)定性對光和溫度敏感
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