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1047634-63-8

中文名稱 AFURESERTIB (GSK2110183)
英文名稱 GSK2110183
CAS 1047634-63-8
分子式 C18H16Cl2F2N4OS
分子量 445.31
MOL 文件 1047634-63-8.mol
更新日期 2025/01/14 17:14:46
1047634-63-8 結(jié)構(gòu)式 1047634-63-8 結(jié)構(gòu)式

基本信息

中文別名
N-[(1S)-2-氨基-1-[(3,4-二氟苯基)甲基]乙基]-5-氯-4-(4-氯-1-甲基-1H-吡唑-5-基)-2-噻吩甲酰胺
英文別名
CS-1729
GSK2110183
Afuresertib-F free base
Afuresertib (GSK2110183)
GSK2110183
GSK 2110183
GSK-2110183
N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)thiophene-2-carboxamide
(S)-N-(1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
N-[(1S)-2-Amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide
2-Thiophenecarboxamide, N-[(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-
所屬類別
生物化工:激動劑抑制劑

物理化學(xué)性質(zhì)

儲存條件-20°C儲存
溶解度溶于二甲基亞砜

應(yīng)用領(lǐng)域

用途一
Afuresertib-F is an analogue of Afuresertib with one more flurorine-atom compared to its parent drug Afuresertib. Afuresertib-F is an ATK inhibitor. Afuresertib, also known as GSK-2110183 or GSK-2110183C, is an cancer drug candidate under clinical trial.
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