| Identification | More | [Name]
5,6,7-TRIMETHOXYFLAVONE | [CAS]
973-67-1 | [Synonyms]
5,6,7-TRIMETHOXYFLAVONE
BAICALEIN-5,6,7-TRIMETHYL ETHER
BAICALEIN TRIMETHYL ETHER
5,6,7-Trimethoxyflavone,97%
2-Phenyl-5,6,7-trimethoxy-4H-1-benzopyran-4-one
5,6,7-Trimethoxy-2-phenyl-4H-1-benzopyran-4-one | [Molecular Formula]
C18H16O5 | [MDL Number]
MFCD00017457 | [Molecular Weight]
312.32 | [MOL File]
973-67-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
165-167°C | [Boiling point ]
497.4±45.0 °C(Predicted) | [density ]
1.242±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 33.33 mg/mL (106.72 mM; Need ultrasonic) | [form ]
Solid | [color ]
White to light yellow | [LogP]
2.990 (est) | [CAS DataBase Reference]
973-67-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 |
| Hazard Information | Back Directory | [Uses]
5,6,7-Trimethoxyflavone is a novel p38-α MAPK inhibitor with an anti-inflammatory effect. 5,6,7-Trimethoxyflavone is isolated from several plants including Zeyhera tuberculosa, Callicarpa japonica, and Kickxia lanigera[1]. | [Definition]
ChEBI: A trimethoxyflavone that is the 5,6,7-trimethyl ether derivative of baicalein. It has been isolated from the plant Callicarpa japonica and has been shown to exhibit antiviral activity. | [References]
[1] Hassan AHE, et al. Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators. Eur J Med Chem. 2019 Jul 9;180:253-267. DOI:10.1016/j.ejmech.2019.07.030 |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
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Energy Chemical
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021-021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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