| Identification | More | [Name]
(+/-)-alpha-Lipoamide | [CAS]
940-69-2 | [Synonyms]
1,2-DITHIOLANE-3-VALEROYLAMIDE
5-(1,2-dithiolan-3-yl)valeramide
6-THIOCTIC AMIDE
A-LIPOIC ACID AMIDE
ALPHA-LIPOAMIDE
ALPHA-LIPOIC AMIDE
DL-6,8-EPIDITHIOOCTANAMIDE
DL-6,8-THIOCTAMIDE
DL-6,8-THIOCTIC ACID AMIDE
DL-6,8-THIOCTIC ACID AMIDE OXIDIZED FORM
DL-ALPHA-LIPOAMIDE
DL-LIPOAMIDE OXIDIZED FORM
DL-THIOCTAMIDE
THIOCTAMIDE
THIOCTIC ACID AMIDE, DL-6,8-
1,2-dithiolane-3-pentanamide
1,2-dithiolane-3-valeramide
alpha-lipamide
alpha-lipoicacidamide
lipamide | [EINECS(EC#)]
213-375-2 | [Molecular Formula]
C8H15NOS2 | [MDL Number]
MFCD00005475 | [Molecular Weight]
205.34 | [MOL File]
940-69-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
127-129 °C(lit.)
| [Boiling point ]
399.2±11.0 °C(Predicted) | [density ]
1.1989 (rough estimate) | [refractive index ]
1.5364 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
Dichloromethane (Slightly), DMSO (Slightly, Heated, Sonicated), Ethanol (Slightly) | [form ]
Solid | [pka]
16.59±0.40(Predicted) | [color ]
Pale Yellow to Yellow | [CAS DataBase Reference]
940-69-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
JP1185000
|
| Hazard Information | Back Directory | [Uses]
(±)-α-Lipoamide may be used in treatment of insulin resistance by stimulating mitochondrial biogenesis. When used in combination with Alprostadil, it has shown to have a good therapeutic effect on early diabetic nephropathy. | [Definition]
ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of lipoic acid with ammonia. | [storage]
Store at -20°C | [Purification Methods]
DL--Lipoamide is recrystallised from EtOH and has UV with max 331nm in MeOH. [Reed et al. J Biol Chem 232 143 1958, IR: Wagner et al. J Am Chem Soc 78 5079 1956, Beilstein 19/7 V 238.] |
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