| Identification | More | [Name]
Creatine phosphate disodium salt | [CAS]
922-32-7 | [Synonyms]
(1-METHYL-4-OXO-2-IMIDAZOLIDINYLIDENE)PHOSPHORAMIDIC ACID DISODIUM SALT
CP
CREATINE PHOSPHATE DISODIUM
CREATINE PHOSPHATE, DISODIUM SALT
CREATINE PHOSPHATE NA
CREATINE PHOSPHATE, NA2
CREATINE PHOSPHATE SODIUM SALT
CREATININE PHOSPHATE DISODIUM SALT
(N-[IMINO-(PHOSPHONO-AMINO)METHYL]-N-METHYLGLYCINE), DISODIUM SALT
PHOSPHOCREATINE, 2NA
PHOSPHOCREATINE, DISODIUM
PHOSPHOCREATINE DISODIUM SALT
PHOSPHOCREATINE, NA2
PHOSPHO CREATINE SODIUM
PHOSPHOCREATINE SODIUM SALT
PHOSPHOCREATININE DISODIUM SALT
SODIUM CREATINE PHOSPHATE
SODIUM PHOSPHOCREATINE
Creatinephosphoricaciddisodiumsalttetrahydrate
n-[imino(phosphonoamino)methyl]-n-methyl-glycindisodiumsalt | [EINECS(EC#)]
213-074-6 | [Molecular Formula]
C4H8N3Na2O5P | [MDL Number]
MFCD00014351 | [Molecular Weight]
255.08 | [MOL File]
922-32-7.mol |
| Chemical Properties | Back Directory | [Appearance]
white powder | [density ]
1.784 at 20℃ | [vapor pressure ]
0.025Pa at 20-50℃ | [storage temp. ]
2-8°C
| [solubility ]
H2O: 0.1 g/mL, clear, colorless
| [form ]
Powder | [color ]
White | [PH]
pH : 8.3 (20% in water) | [Water Solubility ]
soluble | [InChIKey]
HUWYWJSJJDCZRQ-UHFFFAOYSA-L | [LogP]
-1.17 at 22℃ and pH7 | [Surface tension]
68.63mN/m at 1.034g/L and 20℃ | [CAS DataBase Reference]
922-32-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
10 | [HS Code ]
29252900 |
| Questions And Answer | Back Directory | [Description]
Creatine phosphate belongs to the human body and is the most important type of energy supplier. It can provide energy support for various tissues and organs. In human brain, kidney, cardiac muscle and skeletal muscle, 80% of the energy source is creatine phosphate. In humans, the synthesis of creatine phosphate begins in the kidney organs. A guanidinic acid is formed from arginine and glycine, and then creatine is formed through methylation in the liver. Finally, it is phosphorylated in various cellular tissues. And creatine phosphate is formed. Creatine phosphate disodium salt is a commercial creatine phosphate drug, which has become more and more widely used in acute myocardial infarction in recent years, and has achieved good results.
| [Uses]
Creatine phosphate disodium salt is a white needle-like crystalline powder that is easily soluble in water. In medicine, it can protect the heart muscle by injecting creatine phosphate disodium salt, and can also be used to treat myocardial abnormalities in the ischemic state. creatine phosphate plays an important role in energy metabolism during muscle contraction[3]. The use of creatine phosphate is generally by intravenous injection. Phosphocreatine disodium salt exists as creatine phosphate after entering the body.
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| Hazard Information | Back Directory | [Chemical Properties]
white powder | [storage]
Store at -20°C | [Purification Methods]
The salt first appears as oily droplets which slowly settle and crystallise. After 12hours the supernatant is clear. Stirring and scratching the flask containing the filtrate brings out additional crystals (0.3-1g) if the salt is kept at 20o for 12hours. Filter it off at room temperature, wash with 3 x 5mL of ice-cold 90% EtOH, then 5mL of absolute EtOH and dry it in a vacuum desiccator (Drierite or CaCl2) for 16-30hours. The hexahydrate (plates) is converted to the tetrahydrate salt (needles) in a vacuum at -10o. [Ennor & Stocken Biochemical Preparations 5 9 1957, Biochem J 43 190 1958, Beilstein 4 III 1170, 4 IV 2425.] |
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