| Identification | More | [Name]
Scopoletin | [CAS]
92-61-5 | [Synonyms]
6-METHOXYCOUMARIN
6-METHOXYUMBELLIFERONE
7-HYDROXY-5-METHOXYCOUMARIN
7-HYDROXY-6-METHOXY-2H-1-BENZOPYRAN-2-ONE
7-HYDROXY-6-METHOXY-2H-CHROMEN-2-ONE
7-HYDROXY-6-METHOXYCOUMARIN
AKOS 214-14
B-METHYLESCULETIN
CHRYSATROPIC ACID
ESCULETIN-6-METHYL ETHER
GELSEMINIC ACID
MURRAYETIN
SCOPOLETIN
2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-
6-Methoxy-7-hydroxycoumarin
6-Methylesculetin
6-O-Methylesculetin
7-hydroxy-6-methoxy-2h-1-benzopyran-2-on
7-hydroxy-6-methoxy-coumari
beta-Methylesculetin | [EINECS(EC#)]
202-171-9 | [Molecular Formula]
C10H8O4 | [MDL Number]
MFCD00006872 | [Molecular Weight]
192.17 | [MOL File]
92-61-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
203-205 °C (lit.) | [Boiling point ]
288.14°C (rough estimate) | [density ]
1.2932 (rough estimate) | [refractive index ]
1.5430 (estimate) | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Sightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Heated) | [form ]
Crystalline Powder | [pka]
7.91±0.20(Predicted) | [color ]
Beige | [Water Solubility ]
Slightly soluble | [Usage]
The aglucone of Scopolin. Used for cosmetics, topical formulations, and foods. | [Merck ]
8408 | [BRN ]
156296 | [InChIKey]
RODXRVNMMDRFIK-UHFFFAOYSA-N | [LogP]
1.280 (est) | [CAS DataBase Reference]
92-61-5(CAS DataBase Reference) | [NIST Chemistry Reference]
7-Hydroxy-6-methoxy-2h-1-benzopyran-2-one(92-61-5) | [EPA Substance Registry System]
92-61-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
2
| [RTECS ]
GN6930000
| [HS Code ]
29322090 |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Scopoletin can be used for cosmetics, topical formulations, and foods.
| [Definition]
ChEBI: A hydroxycoumarin that is umbelliferone bearing a methoxy substituent at position 6. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 27, p. 3083, 1962 DOI: 10.1021/jo01056a023 | [General Description]
Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species. | [Biochem/physiol Actions]
Scopoletin significantly increases activity of lipoprotein lipase in adipocytes by promoting transcription of the LPL gene. It also partially reverses inhibition of LPL by TNF-α. | [Purification Methods]
Crystallise it from water, acetic acid or *C6H6/MeOH. It is dimorphic with a second m at 193-195o. It sublimes at 120-130o/12mm. [Beilstein 18 H 99, 18 I 348, 18 II 68, 18 III/IV 1323, 18/3 V 203.] |
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