| Identification | More | [Name]
2-Ethylphenol | [CAS]
90-00-6 | [Synonyms]
2-ETHYLPHENOL
O-ETHYLPHENOL
ORTHO-ETHYLPHENOL
PHLOROL
1-ethyl-2-hydroxy-benzen
1-Ethyl-2-hydroxybenzene
1-ethylphenol
1-Hydroxy-2-ethylbenzene
2-ethyl-pheno
Ethylphenol
o-ethyl-pheno
Phenol, o-ethyl-
Phenol,2-ethyl-
Phenol,o-ethyl-
2-Ethylphenol o-Ethylphenol
2-ETHYLPHENOL PESTANAL
2-Ethylphenol,98% | [EINECS(EC#)]
201-958-4 | [Molecular Formula]
C8H10O | [MDL Number]
MFCD00002249 | [Molecular Weight]
122.16 | [MOL File]
90-00-6.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid | [Melting point ]
-18 °C (lit.) | [Boiling point ]
195-197 °C (lit.) | [density ]
1.037 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.536(lit.)
| [Fp ]
78 °C
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
clear liquid | [pka]
pK1:10.2 (25°C) | [color ]
Colorless to Light yellow | [Stability:]
Stable. Combustible. Incompatible with acid chlorides, acid anhydrides, oxidizing agents. | [Water Solubility ]
insoluble | [Merck ]
14,3839 | [BRN ]
1099397 | [LogP]
2.470 | [CAS DataBase Reference]
90-00-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Phenol, 2-ethyl-(90-00-6) | [EPA Substance Registry System]
90-00-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi,C | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R34:Causes burns.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 3145 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
SL4025000
| [F ]
8 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29071900 | [Safety Profile]
Poison by intraperitoneal route. Moderately toxic by ingestion. Human toxic action similar to, but less severe than, that of phenol. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also PHENOL | [Hazardous Substances Data]
90-00-6(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Chemical Properties]
colourless liquid | [Uses]
2-Ethylphenol is used as a reagent in the synthesis of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists used in the treatment of diabetes. It is also used in the preparation of aminoquinazolines as Toll-like receptor 4 ligands and potential immunotherapeutics. | [Definition]
ChEBI: 2-Ethylphenol is a member of phenols. | [Preparation]
2-Ethylphenol is produced by ethylation of phenol using ethylene or ethanol in the presence of aluminium phenolate. It is a natural product found in Cichorium endivia, Saussurea involucrata, and other organisms with data available. | [Purification Methods]
Purify as for p-ethylphenol below. [Beilstein 6 H 470, 6 IV 3011.] |
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