| Identification | More | [Name]
2-Chlorobenzaldehyde | [CAS]
89-98-5 | [Synonyms]
2-CHLOROBENZALDEHYDE
AKOS BBS-00003191
OCAD
O-CHLOROBENZALDEHYDE
o-Chlorobenzenecarboxyaldehyde
2-chloorbenzaldehyde
2-Chlorbenzaldehyd
2-chloro-benzaldehyd
2-Clorobenzaldeide
Benzaldehyde, o-chloro-
Benzaldehyde,2-chloro-
-Chloroformylbenzene
o-Chloorbenzaldehyde
o-Chlor-benzaldehyd
o-chloro-benzaldehyd
o-Chlorobenzenecarboxaldehyde
USAF m-7
usafm-7
o-Chlorobenzaldehyde 2-Chlorobenzaldehyde
ORTHO CHLORO BENZALDEHYDE | [EINECS(EC#)]
201-956-3 | [Molecular Formula]
C7H5ClO | [MDL Number]
MFCD00003304 | [Molecular Weight]
140.57 | [MOL File]
89-98-5.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless to brown liquid | [Melting point ]
9-11 °C (lit.) | [Boiling point ]
209-215 °C (lit.) | [density ]
1.248 g/mL at 25 °C(lit.)
| [vapor density ]
4.84 (vs air)
| [vapor pressure ]
1.27 mm Hg ( 50 °C)
| [refractive index ]
n20/D 1.566(lit.)
| [Fp ]
190 °F
| [storage temp. ]
Store in RT | [solubility ]
1.8g/l | [form ]
Liquid | [color ]
Clear colorless to light yellow | [PH]
2.9 (H2O)(saturated aqueous solution) | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, iron, strong reducing agents. Moisture and light-sensitive. | [Water Solubility ]
0.1-0.5 g/100 mL at 24 ºC | [Sensitive ]
Air Sensitive | [BRN ]
385877 | [LogP]
2.44 at 25℃ | [CAS DataBase Reference]
89-98-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzaldehyde, 2-chloro-(89-98-5) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
89-98-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xi | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3265 8/PG 3
| [WGK Germany ]
1
| [RTECS ]
CU5075000
| [F ]
8-9-23 | [Autoignition Temperature]
746 °F | [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29130000 | [Safety Profile]
Poison by
intraperitoneal and intravenous routes.
When heated to decomposition it emits
toxic fumes of Cl-. See also ALDEHYDES
and CHLORIDES. | [Hazardous Substances Data]
89-98-5(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 2160 mg/kg |
| Hazard Information | Back Directory | [General Description]
Clear colorless to yellowish liquid. | [Reactivity Profile]
2-CHLOROBENZALDEHYDE(89-98-5) reacts with iron and strong oxidizers, strong bases and strong reducing agents. | [Air & Water Reactions]
This chemical is moisture and light sensitive. Slightly water soluble. | [Fire Hazard]
This chemical is combustible. | [Chemical Properties]
colourless to brown liquid | [Uses]
Acid zinc plating brightener, also be used for organic synthesis, agricultural pesticide and pharmaceutical industries.
2-Chlorobenzaldehyde undergoes alkynylation with phenylacetylene in the presence of catalytic ligands and dimethylzinc at 0°C to form binaphthyl-derived amino alcohols.
2-Chlorobenzaldehyde has been used in generation of small focused library of diversely functionalized dihydropyrimidine derivatives via one-pot three-component Biginelli cyclocondensation of β-ketoesters, aldehydes and thioureas. | [Application]
2-Chlorobenzaldehyde is used acid zinc plating brightener, also be used for organic synthesis, agricultural pesticide and pharmaceutical industries. It is used to synthesize the acaricides clofentezine and flutenzine. 2-Chlorobenzaldehyde undergoes alkynylation with phenylacetylene in the presence of catalytic ligands and dimethylzinc at 0°C to form binaphthyl-derived amino alcohols. | [Preparation]
2-Chlorobenzaldehyde is produced mainly by chlorination of 2-chlorotoluene to form 2-chlorobenzal chloride, which is then subjected to acid hydrolysis. Metal salts, such as iron(III) chloride, are used as catalysts. The hydrolysis can also be accomplished using formic acid without a catalyst.
2-Chlorobenzaldehyde can also be produced by oxidation of 2-chlorobenzyl chloride with N-oxides of tertiary amines or with dilute nitric acid.
https://pubchem.ncbi.nlm.nih.gov/compound/2-Chlorobenzaldehyde | [Synthesis Reference(s)]
Tetrahedron Letters, 34, p. 8037, 1993 DOI: 10.1016/S0040-4039(00)61444-2 | [Health Hazard]
Symptoms of exposure to 2-Chlorobenzaldehyde may include skin, eye
and upper respiratory tract irritation. This
compound may cause skin, eye and respiratory tract irritation. When
heated to decomposition it emits toxic fumes. | [Purification Methods]
Wash it with 10% Na2CO3 solution, then fractionally distil it in the presence of a small amount of catechol as stabiliser. [Beilstein 7 H 233, 7 IV 561.] |
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