| Identification | More | [Name]
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE | [CAS]
88519-57-7 | [Synonyms]
W-13
W-13 HYDROCHLORIDE
OMEGA-13 HYDROCHLORIDE
N-(4-AMINOBUTYL)-5-CHLORO-2- &
W-13 HYDROCHLORIDE CALMODULIN ANTAGONIST
W-13, Hydrochloride - CAS 88519-57-7 - Calbiochem
N-(4-aminobutyl)-5-chloro-2-*naphthalenesulfonami
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HCL
4-[(5-chloro-2-naphthalenyl)sulfonylamino]butylammonium
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
N-(4-Aminohexyl)-5-chloro-2-naphthalenesulfonamide hydrochloride
N-(4-AMinobutyl)-5-chloronaphthalene-2-sulfonaMide Hydrochloride
N-(4-Aminobutyl)-5-chloronaphthalene-2-sulphonamide hydrochloride
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENE SULPHONAMIDE, HYDROCHLORIDE
N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide Hydrochloride >
N-(4-AMinobutyl)-5-chloro-2-naphthalenesulfonaMide Monohydrochloride
2-NaphthalenesulfonaMide, N-(4-aMinobutyl)-5-chloro-, Monohydrochloride
N-(4-Aminobutyl)-5-chloronaphthalene-2-sulfonamide Hydrochloride
(+)-5-Hydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one | [Molecular Formula]
C14H18Cl2N2O2S | [MDL Number]
MFCD00058030 | [Molecular Weight]
349.28 | [MOL File]
88519-57-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Beige Solid | [Melting point ]
241-243°C | [storage temp. ]
2-8°C
| [solubility ]
H2O: Stock solutions of 5 mM are recommended. These stocks should be stable for up to 6 months when stored at 4?#x00b0;C.soluble
| [form ]
powder
| [color ]
white
| [Water Solubility ]
water: 35mg/mL | [Usage]
Calmodulin antagonist that binds to calmodulin and inhibits calcium-ion-calmodulin-regulated activities, including phosphodiesterase activation and myosin light chain kinase | [CAS DataBase Reference]
88519-57-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
2935.90.9500 |
| Hazard Information | Back Directory | [Description]
W-13 is a naphthalenesulfonamide derivative that acts as a potent antagonist of calmodulin (IC50 = 22 μM) and is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.1,2,3 | [Chemical Properties]
Beige Solid | [Uses]
Calmodulin antagonist that binds to calmodulin and inhibits calcium-ion-calmodulin- regulated activities, including phosphodiesterase activation and myosin light chain kinase127, it is widely used to investigate Ca2+/calmodulin-regulated enzyme activities.
| [Uses]
W-13 is a naphthalenesulfonamide derivative that acts as a potent antagonist of calmodulin (IC50 = 22 μM) and is widely used to investigate Ca2+/calmodulin-regulated enzyme activities. | [Definition]
ChEBI:N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide hydrochloride is a hydrochloride salt prepared from equimolar amounts of N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide and hydrogen chloride. It contains a N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide(1+). | [Biological Activity]
Calmodulin antagonist (inhibits calmodulin activated PDE activity with an IC 50 of 68 μ M). Inhibits growth of tamoxifen-resistant breast cancer cells. | [Biochem/physiol Actions]
W-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells. | [storage]
Store at -20°C |
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