| Identification | More | [Name]
2-Chloroethylamine hydrochloride | [CAS]
870-24-6 | [Synonyms]
2-AMINOETHYL CHLORIDE HYDROCHLORIDE
2-CHLOROETHYLAMINE HCL
2-CHLOROETHYLAMINE HYDROCHLORIDE
2-CHLOROETHYLAMINE MONOHYDROCHLORIDE
2-CHLOROETHYLAMINO HYDROCHLORIDE
2-CHLOROETHYLAMMONIUM CHLORIDE
BETA-AMINOETHYL CHLORIDE HYDROCHLORIDE
BETA-CHLOROETHYLAMINE HYDROCHLORIDE
CHLOROETHYLAMINE HYDROCHLORIDE
2-chloro-ethanaminhydrochloride
2-chloro-ethylaminhydrochloride
Ethanamine,2-chloro-,hydrochloride
2-Chloroethylamine HCl anhyd.
2-CHLOROETHYLAMINE MONOHYDROCHLORIDE, 99 %
2-CHLOROPROPYLAMINE·HCL
2-ChloroethylamineHcl99%
2-ChloroethylamineHydrochloride98%
2-CHLOROETHYLAMINE HYDROCHLORIDE (CEA)
2-CHLOROETHYLAMINE HYDROCHLORIDE (70% SOLUTION) (CEA LIQ)
2-Chloroethylamine hydrochloride, 70 wt.% aqueous solution | [EINECS(EC#)]
212-793-2 | [Molecular Formula]
C2H7Cl2N | [MDL Number]
MFCD00012887 | [Molecular Weight]
115.99 | [MOL File]
870-24-6.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE TO LIGHT BEIGE CRYSTALLINE POWDER | [Melting point ]
140-150 °C(lit.)
| [storage temp. ]
Store below +30°C. | [solubility ]
5666g/l | [form ]
Crystalline Powder | [color ]
White to light beige | [PH]
2-3 (5666g/l, H2O, 20℃) | [Water Solubility ]
SOLUBLE | [Sensitive ]
Hygroscopic | [BRN ]
3590304 | [InChIKey]
ONRREFWJTRBDRA-UHFFFAOYSA-N | [CAS DataBase Reference]
870-24-6(CAS DataBase Reference) | [EPA Substance Registry System]
870-24-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
UN3261 | [WGK Germany ]
3
| [RTECS ]
KR1800000
| [F ]
3-10-34 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29211980 | [Toxicity]
LD50 orally in Rabbit: > 2000 mg/kg |
| Questions And Answer | Back Directory | [Chemical Properties]
2-Chloroethylamine hydrochloride (C2H7Cl2N, CAS registry No. 870-24-6) is a white to light beige crystalline powder. It is soluble in water and stable at room temperature in closed containers under normal storage and handling conditions. It should store in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances and should be protected from moisture.
| [Application]
2-Chloroethylamine hydrochloride is an important fine chemical intermediate. It can be used for the synthesis of fluvoxamine maleate, which is an important antidepressant drug. 2-Chloroethylamine hydrochloride can also be used as the substrate to synthesize 2-(2'-Aminoaryl)oxazolines and their derivatives, which have been studied as ligands for a variety of metal chelates and are known to possess biological activity in both free ligand and chelated forms. Meanwhile, 2-chloroethylamine hydrochloride can be used for chemical modification of chitosan to improve the biological activity of chitosan.
2-Chloroethylamine hydrochloride can also react with hydroxypropyl starch (HPS) to form aminoethyl hydroxypropyl starch (AEHPS), which can react with collagen peptide (COP) by using microbial transglutaminase (MTGase) as biocatalyst to synthesize aminoethyl hydroxypropyl starch collagen peptide (AEHPS-COP). The AEHPS-COP showed a promising potential application in cosmetic, biomedical and pharmaceutical fields with improved in vitro antioxidant activities.
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| Hazard Information | Back Directory | [Uses]
2-chloroethylamine hydrochloride is used as an intermediate in active pharmaceutical ingredients and dyes. It is also used in organic synthesis. Further, it is employed as a derivatizing reagent for amino acids, dipeptides and nucleotides. |
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