| Identification | More | [Name]
L(+)-Tartaric acid | [CAS]
87-69-4 | [Synonyms]
2,3-DIHYDROXYBUTANEDIOIC ACID
2,3-DIHYDROXYDUTANEDIOIC ACID
(2R,3R)-2,3-DIHYDROXYSUCCINIC ACID
(2R,3R)-(+)-TARTARIC ACID
ACIDUM TARTARICUM
DEXTROTARTARIC ACID
DIHYDROXYSUCCINIC ACID
D-TARTARIC ACID
FEMA 3044
L-2,3-DIHYDROXYBUTANEDIOIC ACID
L-2,3-DIHYDROXYSUCCINIC ACID
L(+)-DIHYDROXYSUCCINIC ACID
(+)-L-TARTARIC ACID
L-(+)-TARTARIC ACID
L-TARTARIC ACID
L-THREACRIC ACID
NATURAL TARTARIC ACID
(R,R)-TARTARIC ACID
(+)-TARTARIC ACID
TARTARIC ACID | [EINECS(EC#)]
201-766-0 | [Molecular Formula]
C4H6O6 | [MDL Number]
MFCD00064207 | [Molecular Weight]
150.09 | [MOL File]
87-69-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white crystals | [Melting point ]
170-172 °C(lit.)
| [alpha ]
12 º (c=20, H2O) | [Boiling point ]
191.59°C (rough estimate) | [density ]
1.76 | [vapor density ]
5.18 (vs air)
| [vapor pressure ]
<5 Pa (20 °C) | [FEMA ]
3044 | [refractive index ]
12.5 ° (C=5, H2O) | [Fp ]
210 °C
| [storage temp. ]
Store at RT. | [solubility ]
H2O: soluble1M at 20°C, clear, colorless | [form ]
Solid | [pka]
2.98, 4.34(at 25℃) | [color ]
White or colorless | [Odor]
at 100.00 %. odorless | [PH]
1.6 (100g/l, H2O, 25℃) | [Stability:]
Stable. Incompatible with oxidizing agents, bases, reducing agents. Combustible. | [Odor Type]
odorless | [optical activity]
[α]20/D +13.5±0.5°, c = 10% in H2O | [Water Solubility ]
1390 g/L (20 ºC) | [Detection Methods]
T,NMR，M.P | [JECFA Number]
621 | [Merck ]
14,9070 | [BRN ]
1725147 | [Dielectric constant]
35.9（-10℃） | [InChIKey]
FEWJPZIEWOKRBE-JCYAYHJZSA-N | [LogP]
-1.43 | [CAS DataBase Reference]
87-69-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Butanedioic acid, 2,3-dihydroxy-[r-(r*,r*)]-(87-69-4) | [EPA Substance Registry System]
87-69-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
WW7875000
| [Autoignition Temperature]
797 °F | [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29181200 | [Safety Profile]
Moderately toxic by intravenous route. Mildly toxic by ingestion. Reaction with silver produces the unstable silver tartrate. When heated to decomposition it emits acrid smoke and irritating fumes. |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Hydrogen peroxide | [Preparation Products]
5-Azaindole-->D-(-)-Tartaric Acid-->Tri(o-tolyl)phosphine-->(R)-(-)-3-Quinuclidinol-->L-1-Phenylethylamine-->(R)-(+)-BORNYLAMINE-->(S)-1-Boc-3-(hyroxymethyl)piperidine-->(+)-(3R,4R)-BIS(DIPHENYLPHOSPHINO)-1-BENZYLPYRROLIDINE-->(+)-DIOP-->1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL--->(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine-->Levosulpiride-->(-)-(1S,4R)-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID-->trans-2,5-Dimethylpiperazine-->2-[3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol-->(R)-3-Quinuclidinol hydrochloride-->Ammonium L-tartrate-->Levamisole hydrochloride-->1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI)-->(1R,2R)-(-)-1,2-Diaminocyclohexane-->(+)-Taddol-->(1S,2S)-(+)-1,2-Diaminocyclohexane-->METARAMINOL-->(1R,2R)-(+)-1,2-Diaminocyclohexane L-tartrate |
| Hazard Information | Back Directory | [Chemical Properties]
Tartaric acid occurs as colorless monoclinic crystals, or a white or almost white crystalline powder. It is odorless, with an extremely tart taste. L-(+)-Tartaric Acid is a naturally occurring chemical compound found in berries, grapes and various wines. It provides antioxidant properties and contributes to the sour taste within these products. | [Uses]
In the soft drink industry, confectionery products, bakery products, gelatin desserts, as an acidulant. In photography, tanning, ceramics, manufacture of tartrates. The common commercial esters are the diethyl and dibutyl derivatives used for lacquers and in textile printing. Pharmaceutic aid (buffering agent). | [Definition]
ChEBI: L-tartaric acid is a tetraric acid that is butanedioic acid substituted by hydroxy groups at positions 2 and 3. It is a conjugate acid of a L-tartrate(1-). It is an enantiomer of a D-tartaric acid. | [Production Methods]
Tartaric acid occurs naturally in many fruits as the free acid or in
combination with calcium, magnesium, and potassium.
Commercially, L-(＋)-tartaric acid is manufactured from potassium
tartrate (cream of tartar), a by-product of wine making.
Potassium tartrate is treated with hydrochloric acid, followed by the
addition of a calcium salt to produce insoluble calcium tartrate.
This precipitate is then removed by filtration and reacted with 70%
sulfuric acid to yield tartaric acid and calcium sulfate. | [General Description]
Tartaric Acid belongs to the group of carboxylic acids, and is abundantly found in grapes and wine. It is widely used in drugs, food, and beverage industry. | [Flammability and Explosibility]
Notclassified | [Pharmaceutical Applications]
Tartaric acid is used in beverages, confectionery, food products, and
pharmaceutical formulations as an acidulant. It may also be used as
a sequestering agent and as an antioxidant synergist. In pharmaceutical
formulations, it is widely used in combination with
bicarbonates, as the acid component of effervescent granules,
powders, and tablets.
Tartaric acid is also used to form molecular compounds (salts
and cocrystals) with active pharmaceutical ingredients to improve
physicochemical properties such as dissolution rate and solubility. | [Biochem/physiol Actions]
L-(+)-Tartaric acid serves as a donor ligand for biological processes. It is used as a food additive in candies and soft drinks to impart a sour taste. | [Safety]
Tartaric acid is widely used in food products and oral, topical, and
parenteral pharmaceutical formulations. It is generally regarded as
a nontoxic and nonirritant material; however, strong tartaric acid
solutions are mildly irritant and if ingested undiluted may cause
gastroenteritis.
An acceptable daily intake for L-(＋)-tartaric acid has not been set
by the WHO, although an acceptable daily intake of up to 30 mg/kg
body-weight for monosodium L-(＋)-tartrate has been established.
LD50 (mouse, IV): 0.49 g/kg | [storage]
The bulk material is stable and should be stored in a well-closed
container in a cool, dry place. | [Incompatibilities]
Tartaric acid is incompatible with silver and reacts with metal
carbonates and bicarbonates (a property exploited in effervescent
preparations). | [Regulatory Status]
GRAS listed. Accepted for use as a food additive in Europe.
Included in the FDA Inactive Ingredients Database (IM and IV
injections; oral solutions, syrups and tablets; sublingual tablets;
topical films; rectal and vaginal preparations). Included in
nonparenteral medicines licensed in the UK. Included in the
Canadian List of Acceptable Non-medicinal Ingredients. |
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