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ChemicalBook--->CAS DataBase List--->83435-67-0

83435-67-0

83435-67-0 Structure

83435-67-0 Structure
IdentificationMore
[Name]

DELAPRIL HCL
[CAS]

83435-67-0
[Synonyms]

DELAPRIL HCL
delapril hydrochloride
Dalapril Hcl
N-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-N-(indan-2-yl)gly cine hydrochloride
Adecut
Cupressin
CV 3317
Glycine, N-(2,3-dihydro-1H-inden-2-yl)-N-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, monohydrochloride, (S)-
Glycine, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)-, monohydrochloride
REV 6000A
Defolder
[Molecular Formula]

C26H32N2O5.HCl
[MDL Number]

MFCD00884619
[MOL File]

83435-67-0.mol
Chemical PropertiesBack Directory
[Melting point ]

166-170℃
[alpha ]

D22 +18.5° (c = 1 in methanol)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[solubility ]

DMSO:174.0(Max Conc. mg/mL);355.82(Max Conc. mM)
[form ]

Solid
[color ]

White to off-white
[CAS DataBase Reference]

83435-67-0(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P280-P305+P351+P338
[RTECS ]

MB9668000
Hazard InformationBack Directory
[Description]

Delapril is a new angiotensin-converting enzyme (ACE) inhibitor useful in the treatment of essential hypertension. Orally administered delapril is a prodrug which is de-esterified to its active diacid metabolite. In hypertensive patients delapril significantly decreased systolic blood pressure and ACE activity 24 hours after dosing without affecting endogeneous creatinine clearance.
[Originator]

Takeda (Japan)
[Uses]

Antihypertensive; enzyme inhibitor (angiotensinconverting).
[Uses]

Delapril Hydrochloride is an angiotensin-converting-enzyme inhibitor (ACE) used as an antihypertensive drug in some European and Asian countries, but not in America.
[Definition]

ChEBI: Delapril hydrochloride is a peptide.
[Brand name]

Adecut
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