| Identification | More | [Name]
2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE | [CAS]
82495-75-8 | [Synonyms]
2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE
SEM-TRIPHENYLPHOSPHONIUM CHLORIDE
-(Trimethylsilyl)ethoxymethyl-triphenylphosphonium chloride
2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride
PHENYL PHOSPHONIUM CHLORIDE
[2-(trimethylsily)ethoxymethyl]triphenylphosphonium.Cl | [Molecular Formula]
C24H30ClOPSi | [MDL Number]
MFCD00043159 | [Molecular Weight]
429.01 | [MOL File]
82495-75-8.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
3 | [HS Code ]
2931.90.6000 |
| Hazard Information | Back Directory | [Physical properties]
mp 165–169 °C. | [Uses]
[2-(Trimethylsilyl)ethoxymethyl]-
triphenylphosphonium chloride is a reagent undergoes deprotonation and yield formation permitting
the construction of enol ethers from aldehydes and ketones. | [Uses]
2-(Trimethylsilyl)ethoxymethyltriphenylphosphonium Chloride is used in preparation of Benzodecalindiones as antitumor agents. | [Preparation]
Involves reaction of triphenylphosphine
with 2-(trimethylsilyl)ethoxymethyl chloride in benzene at gentle
reflux for 18 h. Upon cooling, the resulting phosphonium salt
can be recovered by filtration and purified by triturating with
diethyl ether in 94% yield. | [Purification Methods]
Wash the solid with AcOH and recrystallise it from CH2Cl2/EtOAc. Dry it in a vacuum desiccator. Hygroscopic. 1H NMR (CDCl3) : -0.2 (s, Me3Si), 0.8 (t, 8Hz, CH2Si), 3.83 (t, 8Hz, OCH2), 5.77 (d, JPH 4Hz, P+-CH2O) and 7.70 (m, aromatic H). [Sch.nauer & Zbiral Justus Liebigs Ann Chem 1039 1983.] |
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| Company Name: |
Energy Chemical
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| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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