| Identification | More | [Name]
DL-Norvaline | [CAS]
760-78-1 | [Synonyms]
(+/-)-2-AMINOPENTANOIC ACID
2-AMINOPENTANOIC ACID
DL-2-AMINOPENTANOIC ACID
DL-2-AMINOVALERIC ACID
DL-A-AMINO-N-VALERIC ACID
DL-NORVALINE
H-DL-NVA-OH
NORVALINE, DL-
alpha-DL-Aminopentanoic acid
dl-alpha-Amino-N-valenic acid
DL-alpha-Aminovaleric acid
Valeric acid, 2-amino-, DL-
α-DL-aminopentanoicacid
DL-NORVALINE SIGMA GRADE
DL-NORVALINE 98%
(n)-2-aminopentanoic acid
NORVALINE, DL-(RG)
DL-ALPHA-AMINO-N-VALERICACID
(+/-)-2-Aminopentanoic acid
DL-NORVAALINE | [EINECS(EC#)]
212-082-7 | [Molecular Formula]
C5H11NO2 | [MDL Number]
MFCD00064420 | [Molecular Weight]
117.15 | [MOL File]
760-78-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white to off-white crystals or crystalline powder | [Melting point ]
≥300 °C (dec.) | [Boiling point ]
222.9±23.0 °C(Predicted) | [density ]
1.2000 (estimate) | [refractive index ]
1.4650 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
83.9g/l | [form ]
Solid | [pka]
2.36, 9.72(at 25℃) | [color ]
White to Off-White | [optical activity]
[α]25/D 0.00±0.10°, c = 2 in 5 M HCl | [Water Solubility ]
1 g/10 mL (18 ºC) | [Merck ]
14,6716 | [BRN ]
1721163 | [InChIKey]
SNDPXSYFESPGGJ-UHFFFAOYSA-N | [CAS DataBase Reference]
760-78-1(CAS DataBase Reference) | [NIST Chemistry Reference]
(Dl) 2-aminopentanoic acid(760-78-1) | [EPA Substance Registry System]
760-78-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29224995 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white crystals or crystalline powder | [Uses]
DL-Norvaline has been used as an internal standard:
- to analyze metabolites in cultured mammalian cells by gas chromatography-mass spectrometry (GC-MS)
- to convert cysteine and cystine to Cys MPA (S-2-carboxyethylthio-L-cysteine) and quantify the same using a high-performance liquid chromatography (HPLC) analyzer
- for free amino acid analysis in samples of oocytes by liquid chromatography
| [Uses]
DL-Norvaline is a neurotransmitter. | [Definition]
ChEBI: An alpha-amino acid that is valeric acid which is substituted at position 2 by an amino group. | [General Description]
DL-Norvaline, a non-protein amino acid, is of significance in metabolic pathways. It is used as a food additive on account of its nutritional and functional characteristics that are beneficial to health. | [Biochem/physiol Actions]
Norvaline mediates physiological and pathophysiological processes promoting nitric oxide production. It is used to treat Alzheimer′s disease and is effective against artificial metabolic syndrome in rats. Norvaline exhibits phase transition upon cooling below 190 K and hence it is useful in molecular machines. DL-Norvaline serves as a prototype for research in polymorphism and molecular dynamics of aliphatic α-amino acids containing linear side-chain. It influences the activity, stability, and side-chain packaging of proteins. |
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