| Identification | Back Directory | [Name]
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester | [CAS]
74936-72-4 | [Synonyms]
PRAN-001
278-034-2
Le Chi Chi
1,4-DHPCOOH
Nicardipine USP RC A
Nifedipine Impurity 2
Le Chi mother nucleus
Lercanidipine nucleus
Benidipine Impurity 18
Nimodipine Impurity 7
Lercanidipine mainring
Benidipine Intermediate
Lercanidipine Impurity 9
-2,6-dimethyl-4-(3-nitrophenyl)
Le Cardipine Main Ring Reference
Nicardipine USP Related Compound A
1,4-Dihydro-2,6-dimethyl-4-(3-nitro
-1,4-dihydropyridine-3-carboxylic acid
Nicardipine Carboxylic Acid Derivative
2,6-DI-ME-4-(3-NITRO-PH)-1,4-2H-PYRIDINE-3,5-DICAR
1,4-Dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5-pyr
Nicardipine Carboxylic Acid Derivative (Nifedipine Impurity 2)
Nifedipine Impurity 2 (Nicardipine Carboxylic Acid Derivative )
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
Nicardipine Related Compound A (Nicardipine Carboxylic Acid Impurity)
2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate >
1,4-DIHYDRO-5-METHOXYCARBONYL-2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3-CARBOXYLIC AC
Methyl hydrogen 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
2,6-DiMethyl-5-Methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydorpyridine-3-carboxylic acid
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl ester
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
2,6-DIMETHYL-5-METHOXY CARBONYL-4-(3-NITRO-PHENYL)-1,4-DIHYDROPYRIDINE-3-CARBOXYLIC ACID
2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydroxypyridine-3-carboxylic acid
3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl ester
rac-1,4-Dihydro-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic Acid
2,6-dimethyl-5-methoxycarbonyl-4-(3-nitro phenyl)-1,4 dihydropyridine-3-carboxylic acid (74936-72-4)
PHARMACEUTICAL RAW MATERIAL : 2,6-DIMETHYL-5-METHOXYCARBONYL-4-(3-NITROPHENYL)-1,4- DIHYDROPYRIDINE -3- CARBOXYLIC ACID | [EINECS(EC#)]
278-034-2 | [Molecular Formula]
C16H16N2O6 | [MDL Number]
MFCD00475478 | [MOL File]
74936-72-4.mol | [Molecular Weight]
332.31 |
| Chemical Properties | Back Directory | [Melting point ]
200-202?C | [Boiling point ]
505.0±50.0 °C(Predicted) | [density ]
1.345±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Sparingly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
1.66±0.70(Predicted) | [color ]
Pale Yellow to Light Yellow | [InChI]
InChI=1S/C16H16N2O6/c1-8-12(15(19)20)14(13(9(2)17-8)16(21)24-3)10-5-4-6-11(7-10)18(22)23/h4-7,14,17H,1-3H3,(H,19,20) | [InChIKey]
JPXPPUOCSLMCHK-UHFFFAOYSA-N | [SMILES]
C1(C)NC(C)=C(C(O)=O)C(C2=CC=CC([N+]([O-])=O)=C2)C=1C(OC)=O |
| Hazard Information | Back Directory | [Description]
5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid(1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester) is a pharmaceutical intermediate ingredient used in the preparation of Barnidipine, Lercanidipine hydrochloride and nitrendipine analogues. These drugs are all calcium channel blockers and are used to treat various forms of hypertension. | [Chemical Properties]
Light-Yellow Solid | [Uses]
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester can be used in the prevention and therapy of atherosclerotic degradation of arterial walls.
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