| Identification | More | [Name]
3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid | [CAS]
73463-39-5 | [Synonyms]
3-[CYCLOHEXYLAMINO]-2-HYDROXY-1-PROPANESULFONIC ACID
3-(CYCLOHEXYLAMINO)-2-HYDROXY-1-PROPANESULPHONIC ACID
3-(CYCLOHEXYLAMINO)-2-HYDROXYL-PROPANESULFONIC ACID
3-CYCLOHEXYLAMINO-2-HYDROXY-PROPANE-1-SULFONIC ACID
3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANESULFONIC ACID
CAPSO
CAPSO Free Acid
CAPSO FREE ACID SIGMAULTRA
3-(CYCLOHEXYLAMINO)-2-HYDROXY-1-PROPARESULFONIC ACID
Capso3-(Cyclohexylamino)-2-Hydroxy-1-PropanesulfonicAcid
3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE SULFONIC ACID (CAPSO)
CAPSO, MOLECULAR BIOLOGY GRADE
3-(Cyclohexylamino)-2-hydroxy-
3-(cyclohexylamino)-2-hydroxy-1-propanesuhicic acid (CAPSO) , free acid
CAPSO (3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANESULFONIC ACID)
CAPSO ULTRAPURE
3-(CYCLOHEXYLAMINO)-2-HYDROXY-1-PROPANESUHICICACID(CAPSO)
3-(Cyclohexylamino)-2-hydroxy-1-propanesulphonic acid >97%
3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid, CAPSO Free Acid | [EINECS(EC#)]
615-979-5 | [Molecular Formula]
C9H19NO4S | [MDL Number]
MFCD00041778 | [Molecular Weight]
237.32 | [MOL File]
73463-39-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
270-274°C | [density ]
1.29±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
H2O: 0.1 g/mL, clear, colorless
| [form ]
Powder | [color ]
White | [Odor]
Odorless | [PH Range]
8.9 - 10.3 | [pka]
9.6(at 25℃) | [Water Solubility ]
Soluble in water (10 g+ 90 ml). | [BRN ]
5939234 | [InChI]
InChI=1S/C9H19NO4S/c11-9(7-15(12,13)14)6-10-8-4-2-1-3-5-8/h8-11H,1-7H2,(H,12,13,14) | [InChIKey]
INEWUCPYEUEQTN-UHFFFAOYSA-N | [SMILES]
C(S(O)(=O)=O)C(O)CNC1CCCCC1 | [CAS DataBase Reference]
73463-39-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
3 | [HazardClass ]
IRRITANT | [HS Code ]
29221990 |
| Hazard Information | Back Directory | [Description]
CAPSO is a useful secondary standard buffer. Second dissociation constant pK2 value of CAPSO has been measured. Useful pH range for CAPSO is 8.9 - 10.3.
CAPSO is a biological and zwitterionic buffer commonly categorized as a Good's buffers. CAPSO has many applications some of which include immunoblotting and westerns. Additionally, CAPSO is used in the electrotransfer of proteins to PVDF or nitrocellulose membranes. CAPS buffer has very low metal-binding constants and are, therefore, particularly suited to investigate metal-dependent enzymes. CAPSO a very water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins with minimal salt effects. | [Chemical Properties]
white powder | [Uses]
CAPSO is used in various biological applications such as electrophoresis. Specific applications include buffers for protein separations and diagnostic reagent production. Also used as biological buffer in the following studies, to maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures, chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes, preparation of planar bilayer lipid membranes. | [Uses]
CAPSO was used as biological buffer in the following studies:
To maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures.
Chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes.
Preparation of planar bilayer lipid membranes.
It may be employed as buffer for the electrophoretic analyses in non-denaturing gels, to investigate macromolecular self-association of ADP-ribosyltransferase protein in solution. | [Definition]
ChEBI: 3-(cyclohexylamino)-2-hydroxy-1-propanesulfonic acid is an amine. | [Preparation]
Add sodium sulfite (25.20 g, 0.2 mol) and sodium bisulfite (64.48 g, 0.62 mol) to the three-mouth flask. Heat to dissolve the reactants in water and slowly add epichlorohydrin (50.08 g, 0.54 mol) to the bottle. After vigorous stirring at 30 °C for 2 h, the mixture is cooled in an ice bath. CAPSO is obtained by vacuum suction, drying, and recrystallization. | [General Description]
CAPSO is a useful secondary standard buffer. Second dissociation constant pK2 value of CAPSO has been measured. Useful pH range for CAPSO is 8.9 - 10.3. |
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