| Identification | More | [Name]
2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol | [CAS]
6976-37-0 | [Synonyms]
2,2-BIS(HYDROXYETHYL)-(IMINOTRIS)-(HYDROXYMETHYL)-METHANE
2,2-BIS(HYDROXYMETHYL)-2,2',2''-NITRILOETHANOL
2,2-BIS-(HYDROXYMETHYL)-2,2',2'-NITRILOTRIETHANOL
2,2-BIS(HYDROXYMETHYL)-2,2',2''-NITRILOTRIETHANOL
2-BIS[2-HYDROXYETHYL]AMINO-2-[HYDROXYMETHYL]1,3-PROPANEDIOL
BIS(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE
BIS(2-HYDROXYETHYL)IMINOTRIS(HYDROXYMETHYL)METHANE
BIS(2-HYDROXYETHYL)IMINO-TRIS(HYDROXYMETHYL)PROPANE
BIS(HYDROXYETHYL)IMINO-TRIS-(HYDROXYMETHYL)-METHANE
''BIS-TRIS''
BIS-TRIS
BIS-TRIS BUFFER
2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-3-propanediol
Bis Tris Bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane
Bis Tris, Molecular Biology Grade Bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane, Molecular Biology Grade
Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane~Bis-TRIS
Bis(2-hydroxyethyl)-imino-tris-(hydroxymethyl)-methane biological buffer
bis-tris cell culture tested
bis-tris free base
bis-tris free base sigmaultra | [EINECS(EC#)]
230-237-7 | [Molecular Formula]
C8H19NO5 | [MDL Number]
MFCD00002853 | [Molecular Weight]
209.24 | [MOL File]
6976-37-0.mol |
| Chemical Properties | Back Directory | [Appearance]
White/clear crystalline powder | [Melting point ]
104 °C(lit.)
| [Boiling point ]
466.2±40.0 °C(Predicted) | [density ]
1.346±0.06 g/cm3(Predicted) | [vapor pressure ]
0Pa at 25℃ | [storage temp. ]
Store at RT. | [solubility ]
H2O: 1 M at 20 °C, clear, colorless
| [form ]
Solution | [color ]
Yellow to orange | [Odor]
Odorless | [PH]
9.0-10.1 (20-25℃, 1M in water) | [PH Range]
5.8 - 7.2 | [pka]
6.5(at 25℃) | [biological source]
synthetic | [Water Solubility ]
soluble | [Sensitive ]
Air Sensitive | [λmax]
λ: 280 nm Amax: 0.15 | [Detection Methods]
MP,NMR | [BRN ]
2205275 | [InChIKey]
OWMVSZAMULFTJU-UHFFFAOYSA-N | [LogP]
-2.26 at 20℃ | [CAS DataBase Reference]
6976-37-0(CAS DataBase Reference) | [Storage Precautions]
Air sensitive | [EPA Substance Registry System]
6976-37-0(EPA Substance) | [Absorption]
cut-off at 270nm in H2O at 1M |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R21/22:Harmful in contact with skin and if swallowed .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S22:Do not breathe dust . | [WGK Germany ]
3
| [F ]
10-23 | [TSCA ]
Yes | [HS Code ]
29221980 |
| Hazard Information | Back Directory | [Chemical Properties]
White/clear crystalline powder | [Uses]
It is used as a biological buffer, organic synthesize, chemical & pharmaceutical intermediate. It is suitable for fractionation of hemoglobin. | [Definition]
ChEBI: Bis-tris is a buffer substance useful for calibration of glass electrodes and for the preparation of the biochemical and biological buffer solutions; pKa = 6.46 at 25 ℃. It has a role as a buffer. It is functionally related to a member of tris. | [Flammability and Explosibility]
Notclassified | [Purification Methods]
Crystallise BIS-TRIS from hot 1-butanol and dry it in a vacuum at 25o. N,N-Bis-(2-hydroxyethyl)glycine (BICINE) See in “Amino Acids and Peptides”, Chapter 6. |
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