| Identification | Back Directory | [Name]
Sodium danshensu | [CAS]
67920-52-9 | [Synonyms]
dium danshensu
Sodium danshensu
DANSHENSU SODIUM (RG)
Salvianic acid A sodium
(±)-DanShenSu sodium sal
Salvia natriuretic peptide
Sodium Danshensu 67920-52-9
Salvianic acid A sodium,HPLC≥98%
Sodium 3-(3,4-dihydroxyphenyl)lactate
Sodium 3-(3,4-dihydroxyphenyl)-DL-lactate
sodium D-(+)-β-(3,4-dihydroxyphenyl)lactate
Sodium DL-beta-(3,4-dihydroxyphenyl)lactate
3-(3',4'-Dihydroxyphenyl)lactic acid sodium salt
α,3,4-Trihydroxybenzenepropanoic acid sodium salt
sodium 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate
3,4-Dihydroxyphenyl-α-hydroxypropanoic acid sodium salt
Benzenepropanoic acid, a,3,4-trihydroxy-, sodium salt(1:1)
3,4-Dihydroxyphenyl-.alpha.-hydroxypropanoic acid sodiuM salt
Sodium 3-(3,4-dihydroxyphenyl)lactate, 98%, from Salvia miltiorrhiza Bge. | [EINECS(EC#)]
804-287-0 | [Molecular Formula]
C9H9O5.Na | [MDL Number]
MFCD09037393 | [MOL File]
67920-52-9.mol | [Molecular Weight]
220.155 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
H2O : 100 mg/mL (454.24 mM; Need ultrasonic)DMSO : 100 mg/mL (454.24 mM; Need ultrasonic) | [form ]
powder | [color ]
White-beige |
| Hazard Information | Back Directory | [Description]
Danshensu is a salvianolic acid and the major component of S. miltiorrhiza (Danshen) and has diverse biological activities.1,2,3,4 It reduces expression of the autophagy-associated proteins p62, LC3-II, and Beclin-1 and the apoptosis-related proteins Bax and caspase-3, prevents cardiomyocyte damage, and increases heart rate, coronary flow (CF), and left ventricular developed pressure (LVDP) in an isolated rat heart model of ischemia and reperfusion injury.1 Danshensu (60 mg/kg per day) reduces infarct size and improves left ventricular function in a rat model of myocardial infarction.2 It enhances radiation-induced tumor cell death in a Lewis lung carcinoma mouse xenograft model.3 Danshensu also decreases infarct volume, neuronal apoptosis, production of TNF-α, IL-1β, and IL-6, and superoxide dismutase (SOD) and glutathione peroxidase (GPx) activity in a rat model of cerebral ischemia and reperfusion injury.4 | [Chemical Properties]
White to light brown powder | [Uses]
Sodium Danshensu is exhibits protective effects on the excitotoxicity of monosodium glutamate in the late stage of pregnancy on developing mouse fetal brain. | [target]
Calcium Channel | Potassium Channel | Akt | GSK-3 | Bcl-2/Bax | PI3K |
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