成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook--->CAS DataBase List--->122021-74-3

122021-74-3

122021-74-3 Structure

122021-74-3 Structure
IdentificationBack Directory
[Name]

MAGNESIUM LITHOSPERMATE B 98%
[CAS]

122021-74-3
[Synonyms]

Monomethyl lithospermate B
magnessium lithospermate B
MAGNESIUM LITHOSPERMATE B 98%
magnesium,2-[(E)-3-[3-[1-carboxylato-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl]oxy-3-(3,4-dihydroxyphenyl)propanoate
[Molecular Formula]

C36H28MgO16
[MDL Number]

MFCD00914300
[MOL File]

122021-74-3.mol
[Molecular Weight]

740.903
Chemical PropertiesBack Directory
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[color ]

Light yellow to light brown
Hazard InformationBack Directory
[Uses]

Magnesium Lithospermate B, is a derivative of caffeic acid tetramer and an inhibitor of Na+/K+ ATPase, which can be extracted from Salviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucose-induced intracellular oxidative damage. Magnesium Lithospermate B also suppresses neuroin?ammation and attenuates neurodegeneration[1][2][3].
[in vivo]

Magnesium Lithospermate B (2-8 mg/kg; p.o. once daily for 16 d) reduces the renal damage of oxidative stress through reduction of reactive oxygen species in old rats[1].
Magnesium Lithospermate B (0.5 μg/g; s.c. for 6 weeks) promotes the neurogenesis and improves the memory in PD models[3].

Animal Model:Young (5-month-old) and old (20-month-old) specific-pathogen-free male Sprague-Dawley rats[1]
Dosage:2, 8 mg/kg
Administration:P.o. once daily for 16 days
Result:Reduced the protein expression of major subunits of nicotinamide adenine dinucleotide phosphate oxidase (Nox4 and p22phox), phospho-p38, nuclear factor-kappa B p65, cyclooxygenase-2, and inducible nitric oxide synthase.
Showed lower levels of senescence-related proteins such as p16, ADP-ribosylation factor 6, p53, and p21.
[target]

p65 | NF-kB | TGF-β/Smad | ROS | PDGFR
[References]

[1] Magnesium lithospermate B possesses inhibitory activity on Na+,K+‐ATPase and neuroprotective effects against ischemic stroke
[2] Park CH, et, al. Magnesium Lithospermate B from Salvia miltiorrhiza Bunge Ameliorates Aging-Induced Renal Inflammation and Senescence via NADPH Oxidase-Mediated Reactive Oxygen Generation. Phytother Res. 2017 May;31(5):721-728. DOI:10.1002/ptr.5789
[3] Quan W, et, al. Antioxidant properties of magnesium lithospermate B contribute to the cardioprotection against myocardial ischemia/reperfusion injury in vivo and in vitro. J Tradit Chin Med. 2013 Feb; 33(1): 85-91. DOI:10.1016/s0254-6272(13)60106-5
[4] Zhang Z, et, al. Magnesium lithospermate B promotes proliferation and differentiation of neural stem cells in vitro and enhances neurogenesis in vivo. Tissue Cell. 2018 Aug; 53:8-14. DOI:10.1016/j.tice.2018.05.012
122021-74-3 suppliers list
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: +86-28-82633860; +8618080483897 , +8618080483897
Website: https://www.phytopurify.com
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Mensura Group Limited
Tel: +8618109034517 , +8618109034517
Website: m.is0513.com/manufacturer/mensura%20group%20limited/
Company Name: Shanghai Moqi Biological Technology Co., LTD  Gold
Tel: 021-38218169 13341702378
Website: www.winherb.cn
Company Name: Shenzhen Sungening Bio-Tech Co., Ltd  
Tel: +86-0755-89668383
Website: www.sungening.com/en
Company Name: Shanghai Winherb Medical Technology Co., Ltd.  
Tel: 400-186-5138 13341702378
Website: www.winherb.cn
Company Name: Beijing HuaMeiHuLiBiological Chemical   
Tel: 010-56205725
Website: www.huabeibiochem.com
Company Name: Shanghai BeiZhuo Biotech Co., Ltd.  
Tel: 021-61119791,13386096464
Website: m.is0513.com/ShowSupplierProductsList16081/0.htm
Company Name: Hangzhou J&H Chemical Co., Ltd.  
Tel: 0571-+86-571-87396432
Website: www.jhechem.com
Company Name: Hubei Jusheng Technology Co.,Ltd  
Tel: 027-59599241 18871490274
Website: www.jushengtech.com
Company Name: Wuhan ChemFaces Biochemical Co., Ltd.  
Tel: 18607101326 15172504745
Website: http://www.chemfaces.com
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Website: www.emmx.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 021-61312847; 18021002903
Website: http://www.shyuanye.com
Company Name: Shanghai ChengShao Biological Technology Co., Ltd.  
Tel: 021-61847300 13341622919
Website: m.is0513.com/ShowSupplierProductsList19850/0.htm
Company Name: Shanghai Uteam Biotechnology Co., Ltd.  
Tel: 021-36031160 13311776681
Website: www.shruji.com/
Company Name: Shanghai Biological Technology Development Co., Ltd.  
Tel: 021-69955236-807 13918189704
Website: www.shruji.com/
Company Name: Nanjing Digger Medical Technology Co. Ltd.  
Tel: 025-025-51191215 18013836722
Website: http://www.biaozhunpin.cn
Company Name: Shenzhen Polymeri Biochemical Technology Co., Ltd.  
Tel: +86-400-002-6226 +86-13028896684;
Website: https://www.rrkchem.com
Tags:122021-74-3 Related Product Information
40291-39-2 103986-73-8 102-20-5 103-53-7 3238-60-6

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.