| Identification | Back Directory | [Name]
GOSSYPIN | [CAS]
652-78-8 | [Synonyms]
GOSSYPIN
Nsc656276
Aids032470
Aids-032470
,7-trihydroxy-
COTTON CELLULOSE
GOSSYPIN(P)(CALL)
gossypetin-8-glucoside
3,3',4',5,7,8-Hexahydroxyflavone
gossypin from hibiscus vitifolius*flowers
3,3',4',5,7,8-HEXAHYDROXYFLAVONE 8-GLUCOSIDE
3,3',4',5,7-PENTAHYDROXY-8-O-GLUCOSYLFLAVONE
8-[(β-D-Glucopyranosyl)oxy]-3,3',4',5,7-pentahydroxyflavone
2-(3,4-dihydroxyphenyl)-8-(beta-d-glucopyranosyloxy)-3,5,7-trihydroxy-4h-1-b
4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-(beta-d-glucopyranosyloxy)-3,5
2-(3,4-Dihydroxyphenyl)-8-(β-D-glucopyranosyloxy)-3,5,7-trihydroxy- 4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-(β-D-glucopyranosyloxy)-3,5,7-trihydroxy-
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-(.beta.-D-glucopyranosyloxy)-3,5,7-trihydroxy-
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-4-one | [Molecular Formula]
C21H20O13 | [MDL Number]
MFCD00017429 | [MOL File]
652-78-8.mol | [Molecular Weight]
480.38 |
| Chemical Properties | Back Directory | [Melting point ]
229-230°C | [Boiling point ]
886.0±65.0 °C(Predicted) | [density ]
1.883±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble15mg/mL, clear | [form ]
powder | [pka]
5.70±0.40(Predicted) | [color ]
light yellow to dark green-yellow | [LogP]
-1.320 (est) |
| Hazard Information | Back Directory | [Uses]
antiinflammatory, antiangiogenesis, antineoplastic, inhibits NF-kB cell response | [Definition]
ChEBI: A glycosyloxyflavone that is gossypetin attached to a beta-D-glucopyranosyl residue at position 8 via a glycosidic linkage. | [Biological Activity]
Gossypin is an anti-inflammatory pentahydroxyflavone glucoside isolated from Hibiscus vitifolius th at is used as an herbal remedy for diabetesjaundiceand inflammation. Gossypin potently inhibits human cancer cell proliferationincluding melanoma and glioma cells. Gossypin directly binds and inhibits BRAFV600E and CDK4 kinasesand also regulates Chk1 and Cdc25C in U251 glioma cells. | [storage]
Store at -20°C |
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