| Identification | More | [Name]
1,3-Bis[tris(hydroxymethyl)methylamino]propane | [CAS]
64431-96-5 | [Synonyms]
1,3-BIS[TRIS(HYDROXYMETHYL)METHYLAMINO]PROPANE
BIS-TRIS PROPANE
Bis Tris propane 1,3-Bis[tris(hydroxymethyl)methylamino]propane
bis-tris propane molecular biology*reagent
BIS-Tris Propane, ULTROL Grade
Bistrishydroxymethylmethylaminopropane
2,2'-(propane-1,3-diyldiimino)bis[2-(hydroxymethyl)propane-1,3-diol]
BIS-TRIS PROPANE, BIOTECHNOLOGY PERFORMA NCE CERTIFI
BIS-TRIS PROPANE SIGMAULTRA
BIS-TRISPROPANE,BIOLOGICALBUFFER
1,3-Bis[tris(hydroxymethyl)methylamino]propane >99%
1,3-Bis[tris(hydroxymethyl)methylamino]propane, 98+%
1,3-Bis[tris(hydroxymethyl)methylamino]propane [for Buffer Material]
1,3-Bistris(hydroxymethyl)methylaminoüpropane, 98+%
2,2'-(1,3-Propanediylbisimino)bis[2-(hydroxymethyl)-1,3-propanediol]
2,2'-(1,3-Propanediyldiimino)bis[2-(hydroxymethyl)-1,3-propanediol]
2,2'-[1,3-Propanediylbis(imino)]bis[2-(hydroxymethyl)-1,3-propanediol]
N,N'-(1,3-Propanediyl)bis[N-[1,1-bis(hydroxymethyl)-2-hydroxyethyl]amine]
Trimethylenebis(iminomethanetetrayl)hexakismethanol | [EINECS(EC#)]
264-899-3 | [Molecular Formula]
C11H26N2O6 | [MDL Number]
MFCD00004689 | [Molecular Weight]
282.33 | [MOL File]
64431-96-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
164-165 °C(lit.)
| [Boiling point ]
573.3±50.0 °C(Predicted) | [density ]
1.326±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT. | [solubility ]
H2O: 1 M at 20 °C, clear, colorless
| [form ]
Powder/Solid | [color ]
White | [PH]
9.0-10.1 (20-25℃, 1M in water) | [PH Range]
6.3 - 9.5 | [pka]
(1) 6.8, (2) 9.0(at 25℃) | [Water Solubility ]
Soluble in water. | [BRN ]
1786109 | [InChI]
InChI=1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2 | [InChIKey]
HHKZCCWKTZRCCL-UHFFFAOYSA-N | [SMILES]
C(NC(CO)(CO)CO)CCNC(CO)(CO)CO | [CAS DataBase Reference]
64431-96-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29221990 |
| Hazard Information | Back Directory | [Description]
BIS-TRIS Propane is Good′s buffer. It acts as ligand and forms series of dinuclear hydroxo complexes with Lanthanides(III) in the pH range 7-9. It is useful for diagnostic assay manufacturing industry. | [Chemical Properties]
White powder | [Uses]
BIS-Tris Propane is a buffer that is useful in the pH 6.3 - 9.5 range. This wide buffering range is due to its two pKa values, 6.8 (pKa1) and 9.0 (pKa2), being so close. Because of the wide buffering range, particularly down to pH 6 - 7, this buffer has been used to enhance the stability or activity of restriction enzymes, compared to Tris buffer (which is a poor buffer below pH 7.5 and has a comparatively large change in pKa with temperature). | [Application]
BIS-TRIS Propane may be used in the following studies:
As buffer to investigate the influence of anions with varying nucleophilic properties on the autoxidation of oxymyoglobin (MbO2).
Purification of glucose-binding protein from membranes of Sulfolobus solfataricus.
As buffer during GeO2 mineralisation. | [Definition]
ChEBI: Bis-tris propane is a water-soluble buffer substance used for the preparation of the biochemical and biological buffer solutions; pKa = 6.8 at 20 ℃. It has a role as a buffer. It is functionally related to a member of tris. | [General Description]
BIS-TRIS Propane is Good′s buffer. It acts as ligand and forms series of dinuclear hydroxo complexes with Lanthanides(III) in the pH range 7-9. It is useful for diagnostic assay manufacturing industry. | [Precautions]
This trihydroxyamine analog, also known as bis-tris propane, presents as a white to almost white crystalline powder. Store in a cool and dark place. 1,3-Bis[tris(hydroxymethyl)methylamino]propane is known to be incompatible with oxidizing agents and should not be handled in their vicinity. |
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