| Identification | More | [Name]
3,4-Difluorobenzonitrile | [CAS]
64248-62-0 | [Synonyms]
3,4-DIFLUOROBENZONITRILE
4-CYANO-1,2-DIFLUOROBENZENE
LABOTEST-BB LT00847816
Benzonitrile, 3,4-difluoro-(9CI)
3,4-Difluorobenzonitrile,98%
3,4-Difluorobenzonitrile 98%
Benzonitrile, 3,4-difluoro- | [EINECS(EC#)]
264-751-8 | [Molecular Formula]
C7H3F2N | [MDL Number]
MFCD00011666 | [Molecular Weight]
139.1 | [MOL File]
64248-62-0.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
52-54 °C (lit.) | [Boiling point ]
180 °C | [density ]
1.2490 (estimate) | [Fp ]
157 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to lump | [color ]
White to Light yellow | [BRN ]
2082224 | [InChIKey]
BTBFCBQZFMQBNT-UHFFFAOYSA-N | [CAS DataBase Reference]
64248-62-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 1325 4.1/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Toxic | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29269090 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
3,4-Difluorobenzonitrile has been used in the preparation of:
fluorophenoxy herbicides
fluorine substituted benzyl amides | [Application]
3,4-Difluorobenzonitrile can be used as an intermediate of medicine, pesticide and liquid crystal material.
| [Preparation]
The preparation of 3,4-Difluorobenzonitrile is as follows:To the dry reactor was added 289.6 kg (1.843 kmoles) of 3,4-difluorobenzamide and 800 kg of dichloroethane solution, 241.2 kg (2.02 kmoles) of dichlorosulfoxide and catalyst DMF I.5 And the reaction was carried out at 50 ° C for 5 hours with stirring. After the reaction was complete, the reaction solution was poured into ice water with stirring and the mixture was separated to obtain a crude product having a qualitative content of 96% of 3,4-difluorobenzonitrile 259.1 kg (1.788 kmoles) in 97% yield. The crude product was distilled to give a qualitative content of 99% of 3,4,8-difluorobenzonitrile 248.6 kg (1.77 kmoles) and a distillation yield of 99%.
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