| Identification | Back Directory | [Name]
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester | [CAS]
629664-81-9 | [Synonyms]
XL335
CS-899
Fxr 450
Way 362450
Unii-S6kdm312I5
WAY-362450 (XL335
Turofexorate isopropyl
WAY-362450 >=98% (HPLC)
WAY362450 - FXR450 - XL335
XL335;TUROFEXORATE ISOPROPYL
Turofexorate isopropyl [usan]
Turofexorate Isopropyl (XL335)
XL335; WAY 362450; TUROFEXORATE ISOPROPYL; WAY-362450
isopropyl 3-(3,4-difluorobenzoyl)-1,1-diMethyl-1,2,3,6-tetrahydr
propan-2-yl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate
Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carbox
Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxyla
isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
(E)-isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,4,5,5a,6,10b-octahydroazepino[4,5-b]indole-5-carboxylate
3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester
Azepino[4,5-b]indole-5-carboxylic acid, 3-(3,4-difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethyl-, 1-methylethyl ester | [Molecular Formula]
C25H24F2N2O3 | [MDL Number]
MFCD13181507 | [MOL File]
629664-81-9.mol | [Molecular Weight]
438.47 |
| Chemical Properties | Back Directory | [Boiling point ]
617.3±55.0 °C(Predicted) | [density ]
1.275 | [storage temp. ]
room temp | [solubility ]
DMSO : 25 mg/mL (57.02 mM; Need ultrasonic) | [form ]
powder | [pka]
16.49±0.60(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Definition]
ChEBI: Turofexorate isopropyl is a member of indoles. | [Biochem/physiol Actions]
WAY-362450 is a potent and selective Farnesoid X receptor (FXR) agonist that lowers total plasma cholesterol (all lipoprotein species). WAY-362450 reduced the levels of high-density lipoprotein cholesterol (HDLc) in Cynomolgus monkeys, mice and hamsters. Apparently HDL lowering is achieved through increased transhepatic cholesterol efflux. | [storage]
Store at -20°C |
|
|