| Identification | Back Directory | [Name]
XL-765,SAR245409 | [CAS]
1123889-87-1 | [Synonyms]
XL765
CS-432
SAR245409
XL-765,SAR245409
XL765(Voxtalisib)
XL-765,SAR245409 USP/EP/BP
N-(4-(N-(3-((3,5-DiMethoxyphenyl)aMino)quinoxalin-2-yl)sulfaMoyl)phenyl)-3-Methoxy-4-MethylbenzaMide
N-[2-[(3,5-Dimethoxyphenyl)amino]quinoxalin-3-yl]-4-[(4-methyl-3-methoxyphenyl)carbonyl]aminophenylsulfonamide | [Molecular Formula]
C31H29N5O6S | [MDL Number]
MFCD25976744 | [MOL File]
1123889-87-1.mol | [Molecular Weight]
599.657 |
| Hazard Information | Back Directory | [Uses]
XL765 is a low-molecular mass PI3K inhibitor that also inhibits DNA-PK and mTOR. | [Definition]
ChEBI: XL765 is a sulfonamide obtained by formal condensation of the sulfonic acid group of 4-[(3-methoxy-4-methylbenzoyl)amino]benzenesulfonic acid with the primary aromatic amino group of N-(3,5-dimethoxyphenyl)quinoxaline-2,3-diamine. A dual PI3K/mTOR inhibitor used in cancer treatment. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, an antineoplastic agent and a mTOR inhibitor. It is a sulfonamide, a quinoxaline derivative, an aromatic amine, a member of benzamides and an aromatic ether. | [target]
p110α |
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