| Identification | More | [Name]
Benzoyl cyanide | [CAS]
613-90-1 | [Synonyms]
alpha-oxophenylacetonitrile
BENZOYL CYANIDE
PHENYLGLYOXYLONITRILE
alpha-oxo-benzeneacetonitril
alpha-Oxobenzeneacetonitrile
alpha-Tolunitrile, alpha-oxo-
Benzeneacetonitrile,alpha-oxo-
Benzeneacetonitrile,a-oxo-
Benzoyl nitrile
Glyoxylonitrile, phenyl-
Oxo(phenyl)acetonitrile
Oxo-phenyl-acetonitrile
Phenylglyoxonitrile
Phenylglyoxynitrile
α-Oxobenzeneacetonitrile
Benzoylcyanide98%
Benzoylcyanide 98%
α-keto-α-tolunitrile
α-oxo-α-tolunitrile
a-Oxobenzeneacetonitrile | [EINECS(EC#)]
210-359-7 | [Molecular Formula]
C8H5NO | [MDL Number]
MFCD00001837 | [Molecular Weight]
131.13 | [MOL File]
613-90-1.mol |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
R25:Toxic if swallowed.
R50:Very Toxic to aquatic organisms.
R34:Causes burns.
R24/25:Toxic in contact with skin and if swallowed .
R20:Harmful by inhalation. | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S29:Do not empty into drains .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 3439 6.1/PG 2
| [WGK Germany ]
3
| [F ]
10 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29269095 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow to brown low melting mass | [Uses]
Using benzoyl cyanide as an electrophile also gives selective acylation of the 3-position, as does levulinic acid in the presence of DCC.
Benzoyl cyanide is used to study the mechanism of reduction of benzoyl cyanide in acetonitrile, N,N-dimethylformamide and acetonitrile. It undergoes hydrolysis by Rhodococcus sp. CCZU10-1 to form benzoylformic acid. Reagent for selective acylation of amino compounds. | [Definition]
ChEBI: Benzoyl cyanide is an alpha-ketonitrile and an aromatic ketone. It is functionally related to a benzoic acid. | [Preparation]
Benzoyl cyanide is prepared by treatment of benzoyl chloride with sodium cyanide under phase-transfer catalytic conditions. This process is also used to convert 4-methyl, 4-methoxy, and 4-chlorobenzoyl chlorides into the corresponding benzoyl cyanides, and similarly cinnamoyl chloride into cinnamoyl cyanide (98%).
| [Synthesis Reference(s)]
Synthetic Communications, 15, p. 849, 1985 DOI: 10.1080/00397918508063881 | [General Description]
Benzoyl cyanide is used to study the mechanism of reduction of benzoyl cyanide in acetonitrile, N,N-dimethylformamide and acetonitrile. It undergoes hydrolysis by Rhodococcus sp. CCZU10-1 to form benzoylformic acid. |
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