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ChemicalBook--->CAS DataBase List--->586-60-7

586-60-7

586-60-7 Structure

586-60-7 Structure
IdentificationBack Directory
[Name]

DYCLONINE
[CAS]

586-60-7
[Synonyms]

dyclonin
yclonine
DYCLONINE
dyclocaine
Dyclonine HCI
DYCLONINE USP/EP/BP
4'-Butoxy-β-piperidinopropiophenone
4’-butoxy-3-piperidino-propiophenon
1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanon
1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one
1-Propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)-
[EINECS(EC#)]

1312995-182-4
[Molecular Formula]

C18H27NO2
[MDL Number]

MFCD00242641
[MOL File]

586-60-7.mol
[Molecular Weight]

289.41
Chemical PropertiesBack Directory
[Boiling point ]

424.5±25.0 °C(Predicted)
[density ]

1.017±0.06 g/cm3(Predicted)
[pka]

8.68±0.10(Predicted)
Hazard InformationBack Directory
[Originator]

Dyclone,Dow,US,1956
[Uses]

anesthetic (local)
[Definition]

ChEBI: N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.
[Manufacturing Process]

A mixture of 17.6 grams of p-n-butoxyacetophenone, 12.1 grams of piperidine hydrochloride, 4.5 grams paraformaldehyde, 0.25 cc concentrated hydrochloric acid, 52.5 cc nitroethane, 7.5 cc of 95% ethanol, and 15 cc of toluene was boiled under reflux for one hour, removing water formed in the reaction by means of a condensate trap. The mixture was then cooled. The crystals which formed were collected by filtration, washed with anhydrous ether and recrystallized from methyl ethyl ketone. The crystals thus obtained, which melted at 174-175°C, were shown by analysis to be 4-n-butoxy-β- piperidinopropiophenone hydrochloride.
[Brand name]

Dyclone (AstraZeneca).
[Therapeutic Function]

Local anesthetic
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