Identification | More | [Name]
2-Amino-4,6-dimethylpyridine | [CAS]
5407-87-4 | [Synonyms]
2-AMINO-4,6-DIMETHYLPYRIDINE 2-AMINO-4,6-LUTIDINE 4,6-DIMETHYL-2-LUTIDINE 4,6-DIMETHYLPYRIDIN-2-AMINE 4,6-DIMETHYL-PYRIDIN-2-YLAMINE 6-AMINO-2,4-LUTIDINE LABOTEST-BB LT00080724 2,4-Lutidine, 6-amino- 2-Amino-4,6-dimethylpuridine 2-amino-4,6-dimethyl-pyridin 4,6-Dimethyl-2-aminopyridine 4,6-dimethyl-2-pyridinamin 4,6-Dimethyl-2-pyridinamine Pyridine, 2-amino-4,6-dimethyl- 4,6-dimethyl-2-pyridylamine 6-AMINO-2,4-LUTIDINE 98+% 2-amino-4,6-dimethylpyridine (6-amino-2,4,-lutidine) 2,4-Dimethyl-6-aminopyridine | [EINECS(EC#)]
226-470-9 | [Molecular Formula]
C7H10N2 | [MDL Number]
MFCD00006322 | [Molecular Weight]
122.17 | [MOL File]
5407-87-4.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
US1818000
| [Hazard Note ]
Irritant | [HS Code ]
2933399990 |
Hazard Information | Back Directory | [Chemical Properties]
White to off-white crystalline | [Uses]
Organic intermediate. | [Application]
2-Amino-4,6-dimethylpyridine is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandins and leukotrienes. 2-Amino-4,6-dimethylpyridine binds to the cyclooxygenase enzyme and blocks its conversion of arachidonic acid to prostaglandin H2. This compound has been shown to have potent inhibitory effects against Leishmania, with high values in reactive compounds. The molecular modeling of this compound shows that it has an unpaired amino function and an amide. | [Purification Methods]
Recrystallise this base from hexane, ether/pet ether or *benzene. Residual *benzene is removed over paraffin-wax chips in an evacuated desiccator. The dipicrate crystallises from EtOH and has m 205-207o(dec). [Beilstein 22 III/IV 4210.] |
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