| Identification | Back Directory | [Name]
1-cinnamoylpyrrolidine | [CAS]
52438-21-8 | [Synonyms]
Cinnamopyrrolidide
1-cinnamoylpyrrolidine
1-[(2E)-1-Oxo-3-phenyl-2-propenyl]pyrrolidine
2-Propen-1-one, 3-phenyl-1-(1-pyrrolidinyl)-, (2E)- | [Molecular Formula]
C13H15NO | [MOL File]
52438-21-8.mol | [Molecular Weight]
201.26 |
| Chemical Properties | Back Directory | [Melting point ]
123℃ | [storage temp. ]
Store at -20°C | [solubility ]
Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble | [form ]
A solid |
| Hazard Information | Back Directory | [Uses]
1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1].
1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2]. | [Definition]
ChEBI: 1-Cinnamoylpyrrolidine is an olefinic compound. It is functionally related to a cinnamic acid. | [storage]
Store at -20°C | [References]
[1] Send toBioorg Med Chem.Ma J, et al. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorg Med Chem. 2004 Jul 15;12(14):3885-9. DOI:10.1016/j.bmc.2004.05.007
[2] Chen IS, et al. Amides with anti-platelet aggregation activity from Piper taiwanense. Fitoterapia. 2007 Sep;78(6):414-9. Epub 2007 May 24. DOI:10.1016/j.fitote.2007.04.009 |
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