| Identification | More | [Name]
4-Iodobenzotrifluoride | [CAS]
455-13-0 | [Synonyms]
1-IODO-4-(TRIFLUOROMETHYL)BENZENE
4-IODO-1-TRIFLUOROMETHYLBENZENE
4-IODO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE
4-IODOBENZOTRIFLUORIDE
4-(TRIFLUOROMETHYL)IODOBENZENE
BUTTPARK 45\01-80
P-IODOBENZOTRIFLUORIDE
P-IODO TRIFLUORO TOLUENE
1-iodo-4-(trifluoromethyl)-benzen
alpha,alpha,alpha-trifluoro-4-iodotoluene
4-Iodobenzotrifluoride,98%
p-Iodine Trifluoro Toluene
4-iodo-à,à,à-trifluorotoluene
4-iodo-α,α,α-trifluorotoluene
4-Iodobenzotrifluoride 98%
4-Iodobenztrifluoride
4-Iodobenzotrifluoride (stabilized with Copper chip)
1-Trifluoromethyl-4-iodobenzene
a,a,a-Trifluoro-p-iodotoluene
4-(Trifluoromethyl)-1-iodobenzene | [EINECS(EC#)]
207-234-4 | [Molecular Formula]
C7H4F3I | [MDL Number]
MFCD00039398 | [Molecular Weight]
272.01 | [MOL File]
455-13-0.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
1760 | [WGK Germany ]
3
| [Hazard Note ]
Toxic/Irritant | [TSCA ]
T | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29039990 |
| Hazard Information | Back Directory | [Chemical Properties]
clear red to pink liquid | [Uses]
4-Iodobenzotrifluoride may be employed as substrate with electron-deficient aromatic ring, during Mizoroki-Heck reaction with acrylic acid, to afford 4-trifluoromethylcinnnamic acid. It undergoes aminocarbonylation in DMF using phosphoryl chloride to give N,N-dimethyl-(4-trifluoromethyl)benzamide. | [Application]
The fluorine atom in the molecular structure of 4-iodotrifluorotoluene makes it have special activity. It is an important pesticide and pharmaceutical intermediate. It can be used as the intermediate of the insecticide fipronil and used for the synthesis of diphenyl ethers containing fluorine herbicide. | [Preparation]
Synthesis of 4-Iodotrifluorotoluene: Prepared by diazotization and iodination of 4-aminobenzotrifluoride or 4-Iodobenzotrifluoride is prepared by direct iodination with trifluorotoluene as raw material. | [General Description]
4-Iodobenzotrifluoride undergoes aminocarbonylation in DMF using phosphoryl chloride to give N,N-dimethyl-(4-trifluoromethyl)benzamide. Mechanism of the copper-free Sonogashira cross-coupling reaction of 4-iodobenzotrifluoride with differently para-substituted phenylacetylenes has been investigated. |
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